Li Katie X, Carducci Nicholas, Moinuddin Omar, Zhou Yunshu, Musch David C, Zacks David N, Besirli Cagri G, Wubben Thomas J
Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.
Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.
Clin Ophthalmol. 2021 Mar 8;15:1013-1022. doi: 10.2147/OPTH.S299762. eCollection 2021.
To investigate the clinical features and surgical outcomes of rhegmatogenous retinal detachment (RRD) associated with giant retinal tears (GRTs) at a tertiary referral center.
A retrospective, non-consecutive interventional case series of GRT-associated RRDs that underwent primary surgical repair at the University of Michigan W.K. Kellogg Eye Center between January 1, 2011 and July 1, 2020. Clinical characteristics and preoperative, perioperative, and postoperative data were collected.
Forty-eight eyes of 47 patients with GRT-associated RRDs met inclusion criteria, including those that were children (under 12 years, N=4, 8.3%), associated with a history of trauma (N=20, 41.7%) or with grade C proliferative vitreoretinopathy (PVR-C) (N=7, 14.6%) at baseline. Median age was 46 years (interquartile range (IQR): 29 years, range: 4 to 72 years), median follow-up was 28 months (IQR: 43 months, range: 3-124 months), and 83.3% (N=40) of subjects were male. Primary surgical repair for GRT-associated RRDs included pars plana vitrectomy (PPV) (N=40, 83.3%), scleral buckle (SB) (N=1, 2.1%), or combined PPV/SB (N=7, 14.6%). Surgical approach commonly involved the use of perfluorocarbon liquid (N=43, 90%) and gas tamponade (N=39, 81%). Single surgery anatomic success (SSAS) was 75% (95% CI: 60%, 85%) at 3 months and 65% (95 CI: 47%, 78%) at 2 years. Final anatomic success was achieved in all 48 eyes (100%). Median visual acuity improved from 20/250 preoperatively to 20/60 at final follow-up, with 44% (N=20) of eyes achieving postoperative visual acuity of 20/40 or better.
In this series from a tertiary referral center, both complex and non-complex GRT-associated RRDs were most commonly managed with PPV alone, perfluorocarbon liquid, and gas tamponade with favorable final anatomic and visual outcomes comparable to other modern GRT series.
在一家三级转诊中心研究与巨大视网膜裂孔(GRT)相关的孔源性视网膜脱离(RRD)的临床特征和手术结果。
对2011年1月1日至2020年7月1日期间在密歇根大学W.K.凯洛格眼科中心接受初次手术修复的GRT相关RRD患者进行回顾性、非连续性介入病例系列研究。收集临床特征以及术前、围手术期和术后数据。
47例GRT相关RRD患者的48只眼符合纳入标准,其中包括儿童(12岁以下,n = 4,8.3%),基线时伴有外伤史(n = 20,41.7%)或C级增殖性玻璃体视网膜病变(PVR-C)(n = 7,14.6%)。中位年龄为46岁(四分位间距(IQR):29岁,范围:4至72岁),中位随访时间为28个月(IQR:43个月,范围:3至124个月),83.3%(n = 40)的受试者为男性。GRT相关RRD的初次手术修复包括玻璃体切割术(PPV)(n = 40,83.3%)、巩膜扣带术(SB)(n = 1,2.1%)或PPV/SB联合手术(n = 7,14.6%)。手术方法通常包括使用全氟碳液体(n = 43,90%)和气液填充(n = 39,81%)。3个月时单次手术解剖成功率(SSAS)为75%(95%CI:60%,85%),2年时为65%(95%CI:47%,78%)。所有48只眼均获得最终解剖成功(100%)。中位视力从术前的20/250提高到最终随访时的20/60,44%(n = 20)的眼术后视力达到20/40或更好。
在这个来自三级转诊中心的系列研究中,复杂和非复杂的GRT相关RRD最常单独采用PPV、全氟碳液体和气液填充进行治疗,最终解剖和视力结果良好,与其他现代GRT系列相当。