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腰多裂肌损伤与退变机制的研究进展

Research Progress on the Mechanism of Lumbarmultifidus Injury and Degeneration.

作者信息

Wang Xianzheng, Jia Rui, Li Jiaqi, Zhu Yibo, Liu Huanan, Wang Weijian, Sun Yapeng, Zhang Fei, Guo Lei, Zhang Wei

机构信息

Department of Spinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050000 Hebei Province, China.

Department of Reproductive Medicine, The Second Hospital of Hebei Medical University, China.

出版信息

Oxid Med Cell Longev. 2021 Feb 26;2021:6629037. doi: 10.1155/2021/6629037. eCollection 2021.

DOI:10.1155/2021/6629037
PMID:33728023
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7936897/
Abstract

This review summarizes recent research progress in the clinical features, image manifestations, and pathological mechanism of multifidus injury. After a brief introduction to the fiber classification, innervation, blood supply, and multifidus function, some factors of multifidus injury, consisting of denervation, intraoperative incision selection and traction, and lumbar degenerative disease are overviewed. In addition, the clinical index of multifidus injury including myoglobin, creatine kinase, IL-6, C-reactive protein, the cross-sectional area of multifidus, the degree of fat infiltration, and intraoperative biopsy are summarized. Furthermore, we recommend that patients with chronic low back pain should take the long-term exercise of lumbodorsal muscles. Finally, some remaining issues, including external fixation and the imaging quantitative evaluation criteria of multifidus, need to be further explored in the future.

摘要

本文综述了多裂肌损伤的临床特征、影像表现及病理机制的最新研究进展。在简要介绍了多裂肌的纤维分类、神经支配、血液供应及功能后,概述了多裂肌损伤的一些因素,包括去神经支配、术中切口选择与牵拉以及腰椎退行性疾病。此外,总结了多裂肌损伤的临床指标,包括肌红蛋白、肌酸激酶、白细胞介素-6、C反应蛋白、多裂肌横截面积、脂肪浸润程度及术中活检。此外,我们建议慢性下腰痛患者应长期进行腰背肌锻炼。最后,一些遗留问题,包括多裂肌的外固定及影像学定量评估标准,未来还需要进一步探索。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc6f/7936897/b8f7e1f89c8b/OMCL2021-6629037.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc6f/7936897/851fad04341e/OMCL2021-6629037.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc6f/7936897/fa026e2095e3/OMCL2021-6629037.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc6f/7936897/b8f7e1f89c8b/OMCL2021-6629037.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc6f/7936897/851fad04341e/OMCL2021-6629037.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc6f/7936897/fa026e2095e3/OMCL2021-6629037.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc6f/7936897/b8f7e1f89c8b/OMCL2021-6629037.003.jpg

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