Lang Corinna N, Zotzmann Viviane, Schmid Bonaventura, Berchtold-Herz Michael, Utzolino Stefan, Biever Paul, Duerschmied Daniel, Bode Christoph, Wengenmayer Tobias, Staudacher Dawid L
Department of Cardiology and Angiology I (Heart Center Freiburg University - Bad Krozingen), Medical Center - University of Freiburg, Faculty of Medicine, Freiburg, DEU.
Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center - University of Freiburg, Faculty of Medicine, Freiburg, DEU.
Cureus. 2021 Feb 7;13(2):e13210. doi: 10.7759/cureus.13210.
Germany reported sufficient intensive care unit (ICU) resources throughout the first wave of coronavirus disease 2019 (COVID-19). The treatment of critically ill COVID-19 patients without rationing may improve the outcome. We therefore analyzed ICU resources allocated to COVID-19 patients with respiratory failure and their outcomes.
Retrospectively, we enrolled severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR)-positive patients with respiratory failure from 03/08/2020 to 04/08/2020 and followed until 05/28/2020 in the university hospital of Freiburg, Germany.
In the defined interval, 34 COVID-19 patients were admitted to the ICU with median age of 67±13 (31-86) years. Six of 34 (17.6%) were female. All patients suffered from moderate or severe acute respiratory distress syndrome (ARDS), 91.2% of the patients were intubated and 23.5% required extracorporeal membrane oxygenation (ECMO). Proning was performed in 67.6%, renal replacement therapy (RRT) was required in 35.3%. Ninety-six percent required more than 20 nursing hours per day. Mean ICU stay was 21±19 (1-81) days. Sixty-day survival of critically ill COVID-19 patients was 50.0% (17/34). Causes of death were multi-organ failure (52.9%), refractory ARDS (17.6%) and intracerebral hemorrhage (17.6%).
Treatment of critically ill COVID-19 patients is protracted and resource-intense. In a context without resources shortage, 50% of COVID-19 with respiratory failure survived up to 60 days.
德国报告称在2019冠状病毒病（COVID-19）的第一波疫情期间，重症监护病房（ICU）资源充足。对重症COVID-19患者进行无配额治疗可能会改善治疗结果。因此，我们分析了分配给呼吸衰竭COVID-19患者的ICU资源及其治疗结果。
我们回顾性纳入了2020年3月8日至2020年4月8日期间在德国弗莱堡大学医院确诊为严重急性呼吸综合征冠状病毒2（SARS-CoV-2）聚合酶链反应（PCR）阳性且伴有呼吸衰竭的患者，并随访至2020年5月28日。
在规定的时间段内，34例COVID-19患者被收入ICU，中位年龄为67±13（31-86）岁。34例患者中有6例（17.6%）为女性。所有患者均患有中度或重度急性呼吸窘迫综合征（ARDS），91.2%的患者接受了气管插管，23.5%的患者需要体外膜肺氧合（ECMO）。67.6%的患者进行了俯卧位通气，35.3%的患者需要肾脏替代治疗（RRT）。96%的患者每天需要超过20小时的护理。ICU平均住院时间为21±19（1-81）天。重症COVID-19患者的60天生存率为50.0%（17/34）。死亡原因包括多器官功能衰竭（52.9%）、难治性ARDS（17.6%）和脑出血（17.6%）。
重症COVID-19患者的治疗过程漫长且资源消耗大。在没有资源短缺的情况下，5
