Klinik für Innere Medizin I, Universitätsklinikum Ulm.
Z Gastroenterol. 2021 Aug;59(8):859-864. doi: 10.1055/a-1401-2170. Epub 2021 Mar 16.
We aimed to determine the prevalence and incidence of gallbladder stones in a random population-based collective in Germany.
We determined the prevalence and incidence rates of gallbladder stones in a random population sample of 1909 individuals from the in Leutkirch (EMIL) study in 2002 and 380 individuals in a follow-up analysis in the year 2013. The sonographic analysis was performed with a Philipps HDI 5000 (2002) and IU 22 (2013) (Netherlands) transducer 1-5 MHz. Statistical analysis was performed using SAS Version 9.4.
The prevalence of gallbladder stones was 3.8 % (69/1909) in 2002 and 10.8 % (41/380) in 2013. In 2013, the gallbladder stone prevalence was 15.1 % (26/172) in women, compared to 7.2 % (15/208) in men. No gallbladder stones were found in participants in the 18-30 or 31-40 age groups. The average annual incidence was 1.03 % in the 41-50 age group, 0.79 % in the 51-65 age group, and 0.63 % in the > 65 age group. The annual incidence was higher among women (1.04 %) than men (0.53 %). The age-associated annual incidence rates for women and men were 1.93 % and 0.5 % in the 41-50 age group, 0.8 % and 0.78 % in the 51-65 age group, and 1.06 % and 0.30 % in the > 65 age group.
For the investigated German collective from 2002 to 2013, the average annual incidence of gallbladder stones was 0.75 %, with a higher incidence rate among women. These results are consistent with data from comparable international studies.
我们旨在确定德国一个随机人群中胆囊结石的患病率和发病率。
我们在 2002 年的 Leutkirch（EMIL）研究中对 1909 名随机人群样本和 2013 年的 380 名随访分析中确定了胆囊结石的患病率和发病率。超声分析使用的是菲利普斯 HDI 5000（2002 年）和 IU 22（2013 年）（荷兰）探头 1-5MHz。统计分析使用 SAS 版本 9.4。
2002 年胆囊结石的患病率为 3.8%（69/1909），2013 年为 10.8%（41/380）。2013 年，女性胆囊结石患病率为 15.1%（26/172），而男性为 7.2%（15/208）。在 18-30 岁或 31-40 岁年龄组的参与者中未发现胆囊结石。41-50 岁年龄组的平均年发病率为 1.03%，51-65 岁年龄组为 0.79%，>65 岁年龄组为 0.63%。女性（1.04%）的年发病率高于男性（0.53%）。女性和男性的年龄相关年发病率在 41-50 岁年龄组分别为 1.93%和 0.5%，51-65 岁年龄组分别为 0.8%和 0.78%，>65 岁年龄组分别为 1.06%和 0.30%。
对于 2002 年至 2013 年期间调查的德国人群，胆囊结石的平均年发病率为 0.75%，女性发病率较高。这些结果与来自可比国际研究的数据一致。
