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心肌顿抑综合征患者的全身炎症:机制与临床意义综述。

Systemic inflammation in patients with Takotsubo syndrome: a review of mechanistic and clinical implications.

机构信息

CardiologyDepartment, Trakya University, Edirne.

Cardiology Department, Derindere Hospital, Istanbul.

出版信息

Monaldi Arch Chest Dis. 2021 Mar 12;91(2). doi: 10.4081/monaldi.2021.1718.

DOI:10.4081/monaldi.2021.1718
PMID:33728882
Abstract

Over recent decades, systemic inflammation  as  quantified  with  inflammation  markers  or  indices has been extensively  investigated  in the setting of  various  cardiovascular  conditions  including heart failure (HF),  acute coronary syndromes (ACS). In contrast, systemic inflammation  in patients with  takotsubo syndrome (TTS) has been an underrated  phenomenon in clinical practice. On the other hand, experimental and clinical data  have been  rapidly  accumulating  in the recent years  regarding   pathogenetic, prognostic as well as therapeutic implications of  systemic inflammation in TTS.  Accordingly, the present article  aims to provide a general perspective  on mechanistic and  clinical aspects of  systemic  inflammation in the setting of  TTS.

摘要

近几十年来,人们广泛研究了各种心血管疾病(包括心力衰竭[HF]和急性冠状动脉综合征[ACS])中用炎症标志物或指数量化的系统性炎症。相比之下,在应激性心肌病(TTS)患者中,系统性炎症在临床实践中一直被低估。另一方面,近年来关于 TTS 中系统性炎症的发病机制、预后和治疗意义的实验和临床数据迅速积累。因此,本文旨在提供一个关于 TTS 中系统性炎症的机制和临床方面的总体观点。

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