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本文引用的文献

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Retinal embolization after carotid endarterectomy and stenting for carotid artery stenosis.颈动脉内膜切除术和支架置入术后治疗颈动脉狭窄引发的视网膜栓塞
J Clin Neurosci. 2015 Aug;22(8):1298-302. doi: 10.1016/j.jocn.2015.01.033. Epub 2015 May 16.
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Local versus general anesthesia for carotid endarterectomy: issues beyond stroke, myocardial infarction, and death rates.颈动脉内膜切除术的局部麻醉与全身麻醉:除中风、心肌梗死和死亡率之外的问题。
Angiology. 2012 Aug;63(6):405-8. doi: 10.1177/0003319711430828. Epub 2011 Dec 30.
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ESVS guidelines. Invasive treatment for carotid stenosis: indications, techniques.欧洲血管外科学会指南。颈动脉狭窄的侵入性治疗:适应症、技术。
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General anaesthesia versus local anaesthesia for carotid surgery (GALA): a multicentre, randomised controlled trial.颈动脉手术全身麻醉与局部麻醉对比研究(GALA):一项多中心随机对照试验
Lancet. 2008 Dec 20;372(9656):2132-42. doi: 10.1016/S0140-6736(08)61699-2. Epub 2008 Nov 27.
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Carotid artery stenting is associated with increased complications in octogenarians: 30-day stroke and death rates in the CREST lead-in phase.颈动脉支架置入术与八旬老人并发症增加相关:CREST导入期的30天卒中及死亡率
J Vasc Surg. 2004 Dec;40(6):1106-11. doi: 10.1016/j.jvs.2004.10.022.
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Protected carotid-artery stenting versus endarterectomy in high-risk patients.高危患者中颈动脉支架置入术与颈动脉内膜切除术的比较
N Engl J Med. 2004 Oct 7;351(15):1493-501. doi: 10.1056/NEJMoa040127.
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Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: randomised controlled trial.在近期无神经系统症状的患者中,通过成功实施颈动脉内膜切除术预防致残性和致命性中风:随机对照试验。
Lancet. 2004 May 8;363(9420):1491-502. doi: 10.1016/S0140-6736(04)16146-1.
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Local versus general anaesthesia for carotid endarterectomy.颈动脉内膜切除术的局部麻醉与全身麻醉
Cochrane Database Syst Rev. 2004(2):CD000126. doi: 10.1002/14651858.CD000126.pub2.
9
Carotid angioplasty and stenting with and without cerebral protection: clinical alert from the Endarterectomy Versus Angioplasty in Patients With Symptomatic Severe Carotid Stenosis (EVA-3S) trial.伴有和不伴有脑保护装置的颈动脉血管成形术和支架置入术:症状性严重颈动脉狭窄患者内膜切除术与血管成形术对比研究(EVA-3S)试验的临床警示
Stroke. 2004 Jan;35(1):e18-20. doi: 10.1161/01.STR.0000106913.33940.DD. Epub 2003 Dec 4.
10
Reconstruction of internal carotid artery in a patient with intermittent attacks of hemiplegia.一名患有间歇性偏瘫发作患者的颈内动脉重建术。
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比较两种不同管理方案对同时需要颈动脉内膜切除术和冠状动脉旁路移植术的患者的影响。

A comparison of two different management plans for patients requiring both carotid endarterectomy and coronary artery bypass grafting.

机构信息

Bilkent City Hospital, Yuksek Ihtısas Cardiovascular Surgery Hospital, Ankara, Turkey. Email:

Department of Cardiovascular Surgery, Medical Faculty of Duzce University, Duzce, Turkey.

出版信息

Cardiovasc J Afr. 2021;32(3):129-132. doi: 10.5830/CVJA-2020-042. Epub 2021 Mar 16.

DOI:10.5830/CVJA-2020-042
PMID:33729273
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8756018/
Abstract

BACKGROUND

Carotid endarterectomy (CEA) is a prophylactic operation that is used to mitigate the risk of stroke caused by embolism of atherosclerotic plaques in the carotid bifurcation. Previously, the large, multicentre, randomised, controlled GALA study found no significant differences in clinical outcomes between patients treated using general or local anaesthesia. While this study provided important insights into disease outcomes based on treatment modalities, it did not answer questions regarding the safety of CEA under local anaesthesia in patients at high risk for cardiovascular complications. Here, we examined the use of two different management plans in patients requiring both carotid endarterectomy and coronary artery bypass grafting (CABG), in terms of their effects on hospital mortality.

METHODS

Thirty-four patients consecutively operated on in our cardiovascular department were included in this analysis. The patients were divided into two groups based on the anaesthetic management plan. The first group consisted of patients who underwent CEA and CABG under general anaesthesia in the same session (GA group); the second group consisted of patients who initially underwent CEA under cervical block anaesthesia followed by CABG under general anaesthesia in a separate session (CB-GA group). These two groups were compared in terms of postoperative complications and hospital mortality.

RESULTS

The incidence of postoperative myocardial infarction was higher in the CB-GA group, with four patients experiencing postoperative myocardial infarction, compared to no patients in the GA group.

CONCLUSIONS

For patients requiring CEA and CABG, performing both operations under general anaesthesia in the same session was safer than initially performing CEA under cervical block anaesthesia followed by CABG under general anaesthesia.

摘要

背景

颈动脉内膜切除术(CEA)是一种预防性手术,用于降低颈动脉分叉处粥样斑块栓塞引起中风的风险。此前,大型、多中心、随机、对照的 GALA 研究发现,使用全身麻醉或局部麻醉治疗的患者在临床结果方面没有显著差异。虽然这项研究基于治疗方式提供了有关疾病结果的重要见解,但它并没有回答关于在心血管并发症高危患者中局部麻醉下进行 CEA 的安全性问题。在这里,我们研究了在需要同时进行颈动脉内膜切除术和冠状动脉旁路移植术(CABG)的患者中使用两种不同管理方案对住院死亡率的影响。

方法

我们分析了在我院心血管科连续手术的 34 例患者。根据麻醉管理计划,患者分为两组。第一组为同时接受全身麻醉下 CEA 和 CABG 的患者(GA 组);第二组为初始接受颈丛阻滞麻醉下 CEA,然后在另一次手术中接受全身麻醉下 CABG 的患者(CB-GA 组)。比较两组患者的术后并发症和住院死亡率。

结果

CB-GA 组术后心肌梗死发生率较高,有 4 例患者发生术后心肌梗死,而 GA 组无患者发生。

结论

对于需要 CEA 和 CABG 的患者,在同一手术中同时进行两种手术比初始进行颈丛阻滞麻醉下 CEA 然后进行全身麻醉下 CABG 更安全。