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《2020年巴西性传播感染防治方案:人类嗜T淋巴细胞病毒(HTLV)感染》

[Brazilian Protocol for Sexually Transmitted Infections 2020: human T cell lymphotropic virus (HTLV) infection].

作者信息

Rosadas Carolina, Brites Carlos, Arakaki-Sánchez Denise, Casseb Jorge, Ishak Ricardo

机构信息

Imperial College London, Department of Infectious Disease, Londres, Reino Unido.

Universidade Federal da Bahia, Faculdade de Medicina, Salvador, BA, Brasil.

出版信息

Epidemiol Serv Saude. 2021 Mar 15;30(spe1):e2020605. doi: 10.1590/S1679-497420200006000015.esp1. eCollection 2021.

Abstract

This manuscript is related to the chapter about human T-cell lymphotropic virus (HTLV) that is part of the Clinical Protocol and Therapeutic Guidelines for Comprehensive Care for People with Sexually Transmitted Infections, published by the Brazilian Health Ministry. HTLV-1/2 infection is a worldwide public health problem and Brazil has the largest number of individuals living with the virus. HTLV-1 causes a variety of clinical manifestations of a neoplastic nature, such as adult leukemia/T-cell lymphoma, and also of an inflammatory nature, such as HTLV-1-associated myelopathy, as well as other manifestations such as uveitis, arthritis and infective dermatitis. These pathologies have high morbidity and mortality and negatively impact the quality of life of infected individuals. This review includes relevant information for health service managers and workers regarding virus transmission modes, diagnosis, treatment and monitoring of individuals living with HTLV-1 and 2 in Brazil.

摘要

本手稿与巴西卫生部发布的《性传播感染患者综合护理临床方案及治疗指南》中关于人类嗜T淋巴细胞病毒(HTLV)的章节相关。HTLV - 1/2感染是一个全球性的公共卫生问题,巴西感染该病毒的人数最多。HTLV - 1会引发多种肿瘤性质的临床表现,如成人白血病/T细胞淋巴瘤,也会引发炎症性质的表现,如HTLV - 1相关脊髓病,以及其他表现,如葡萄膜炎、关节炎和感染性皮炎。这些病症具有高发病率和高死亡率,对感染者的生活质量产生负面影响。本综述为巴西卫生服务管理人员和工作人员提供了有关HTLV - 1和2感染者的病毒传播方式、诊断、治疗及监测的相关信息。

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