Sokołowska Patrycja, Dąbrowa Kajetan, Jarosz Sławomir
Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.
Org Lett. 2021 Apr 2;23(7):2687-2692. doi: 10.1021/acs.orglett.1c00590. Epub 2021 Mar 17.
Chiral photoresponsive host was prepared by a high-yield CsCO-templated macrocyclization. - transforms into long-lived - (25 days) upon irradiation with green light, and the backward transformation is triggered by blue light. Both isomers prefer potassium among alkali metal cations, and - binds cations stronger than - (/ ≤ 4.1). H NMR titration experiments as well as density functional theory studies reveal that sucrose ring oxygen residues and azobenzene nitrogen atoms in contribute to cation coordination.
通过高产率的 CsCO 模板大环化反应制备了手性光响应主体。在绿光照射下，- 转变为长寿命的 -（25 天），而蓝光可触发逆向转变。在碱金属阳离子中，两种异构体都优先选择钾离子，并且 - 比 - 更强烈地结合阳离子（/≤4.1）。1H NMR 滴定实验以及密度泛函理论研究表明，中的蔗糖环氧残基和偶氮苯氮原子有助于阳离子配位。
