Department of Biomedical Sciences, Humanitas University, Milan, Italy.
Department of Ophthalmology, Humanitas Gavazzeni-Castelli, Bergamo, Italy.
PLoS One. 2021 Mar 17;16(3):e0247192. doi: 10.1371/journal.pone.0247192. eCollection 2021.
To introduce a novel method to quantitively analyse in three dimensions traction forces in a vast area of the ocular posterior pole.
Retrospective analysis of 14 eyes who underwent peeling surgery for idiopathic, symptomatic and progressive epiretinal membrane. The technique measures the shift in position of vascular crossings after surgery from a fixed point, which is the retinal pigmented epithelium. This shift is defined as the relaxation index (RI) and represents a measure of the postoperative movement of the retina due to released traction after surgery.
Best-corrected visual acuity was significantly better than baseline at all follow ups while the RI had its maximum value at baseline. Moreover, we found a significant correlation between best-corrected visual acuity at 6 months and RI at baseline.
While all previous published methods focused on bi-dimensional changes observed in a small region, this study introduces a three-dimensional assessment of tractional forces. Future integration of RI into built-in processing software will allow systematic three-dimensional measurement of intraretinal traction.
介绍一种定量分析眼后极大面积牵引的新方法。
回顾性分析 14 只接受特发性、症状性和进行性视网膜内膜剥除手术的眼。该技术通过从固定点(即视网膜色素上皮)测量手术后血管交叉位置的偏移来测量术后视网膜的运动,该偏移定义为弛豫指数(RI),代表手术后由于释放的牵引力而导致的视网膜的术后运动程度。
最佳矫正视力在所有随访中均显著优于基线,而 RI 在基线时达到最大值。此外,我们发现 6 个月时最佳矫正视力与基线时 RI 之间存在显著相关性。
虽然以前所有发表的方法都集中在观察小区域的二维变化,但本研究介绍了一种对牵引力的三维评估方法。未来将 RI 集成到内置处理软件中,将允许对视网膜内牵引力进行系统的三维测量。