*Department of Ophthalmology, University of California San Diego, La Jolla, California; †Department of Ophthalmology, Ludwig-Maximilians University Munich, Munich, Germany; and ‡Department of Ophthalmology, Sanggye Paik Hospital, Inje University, Seoul, South Korea.
Retina. 2014 Apr;34(4):647-54. doi: 10.1097/IAE.0000000000000003.
To evaluate the morphologic restoration of retinal anatomy after surgery for epiretinal membrane (ERM) peeling using spectral domain optical coherence tomography. Correlation of retinal structure with visual outcome.
Retrospective consecutive case series.
Thirty-four consecutive eyes with ERM underwent surgery with 1 year follow-up examination. Spectral domain optical coherence tomography scans were analyzed preoperatively and 1, 3, 6, 9, and 12 months postoperative. Best-corrected visual acuity (BCVA) using Early Treatment Diabetic Retinopathy Study charts was measured at each visit.
All eyes showed a significant improvement of BCVA after ERM peeling (P = 0.002). The time point of BCVA and retinal restoration seen on spectral domain optical coherence tomography occurred simultaneously and varied between individuals (occurrence of BCVA: mean, 4.82 months; retinal restoration: mean, 4.24 months). At 3 months, the retinal anatomical restoration rate was 70% and 88% at 6 months.
Restoration of the retinal anatomical structure predominantly occurs within the first 3 months post-ERM peeling. An improvement of BCVA and anatomical retinal restoration after ERM removal varies in individuals. If retinal layers fully restore in their anatomical structure, BCVA improves at the same time point.
利用频域光相干断层扫描评估外膜剥除术后视网膜解剖结构的形态恢复。视网膜结构与视力结果的相关性。
回顾性连续病例系列。
34 例连续外膜剥除术眼，随访 1 年。术前及术后 1、3、6、9 和 12 个月进行频域光相干断层扫描分析。每次就诊时均使用早期糖尿病视网膜病变研究图表测量最佳矫正视力（BCVA）。
所有眼在进行外膜剥除术后均出现 BCVA 显著提高（P = 0.002）。BCVA 和频域光相干断层扫描上视网膜恢复的时间点同时出现，且因人而异（BCVA 出现时间：平均 4.82 个月；视网膜恢复时间：平均 4.24 个月）。3 个月时，视网膜解剖恢复率为 70%，6 个月时为 88%。
外膜剥除术后视网膜解剖结构的恢复主要发生在术后 3 个月内。外膜剥除术后 BCVA 和视网膜解剖恢复在个体之间存在差异。如果视网膜层完全恢复其解剖结构，BCVA 将在同一时间点提高。
