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KDIGO 临床实践指南:儿童慢性肾脏病 2-5 期及透析患者的钾饮食管理—儿科肾脏营养工作组的实践推荐

The dietary management of potassium in children with CKD stages 2-5 and on dialysis-clinical practice recommendations from the Pediatric Renal Nutrition Taskforce.

机构信息

University Hospital Ghent, Ghent, Belgium.

Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.

出版信息

Pediatr Nephrol. 2021 Jun;36(6):1331-1346. doi: 10.1007/s00467-021-04923-1. Epub 2021 Mar 17.

Abstract

Dyskalemias are often seen in children with chronic kidney disease (CKD). While hyperkalemia is common, with an increasing prevalence as glomerular filtration rate declines, hypokalemia may also occur, particularly in children with renal tubular disorders and those on intensive dialysis regimens. Dietary assessment and adjustment of potassium intake is critically important in children with CKD as hyperkalemia can be life-threatening. Manipulation of dietary potassium can be challenging as it may affect the intake of other nutrients and reduce palatability. The Pediatric Renal Nutrition Taskforce (PRNT), an international team of pediatric renal dietitians and pediatric nephrologists, has developed clinical practice recommendations (CPRs) for the dietary management of potassium in children with CKD stages 2-5 and on dialysis (CKD2-5D). We describe the assessment of dietary potassium intake, requirements for potassium in healthy children, and the dietary management of hypo- and hyperkalemia in children with CKD2-5D. Common potassium containing foods are described and approaches to adjusting potassium intake that can be incorporated into everyday practice discussed. Given the poor quality of evidence available, a Delphi survey was conducted to seek consensus from international experts. Statements with a low grade or those that are opinion-based must be carefully considered and adapted to individual patient needs, based on the clinical judgment of the treating physician and dietitian. These CPRs will be regularly audited and updated by the PRNT.

摘要

患有慢性肾脏病 (CKD) 的儿童常出现电解质紊乱。高钾血症较为常见,随着肾小球滤过率下降而患病率逐渐增加,但也可能发生低钾血症,特别是在存在肾小管疾病和接受强化透析方案的儿童中。对于 CKD 患儿,饮食评估和钾摄入调整至关重要,因为高钾血症可能危及生命。由于饮食钾的调整可能会影响其他营养素的摄入并降低食物的适口性,因此具有一定挑战性。儿科肾脏营养工作组 (PRNT) 是一个由儿科肾脏营养师和儿科肾病学家组成的国际团队,为 CKD 2-5 期和透析患儿 (CKD2-5D) 的钾饮食管理制定了临床实践建议 (CPR)。我们描述了 CKD2-5D 患儿钾饮食摄入评估、健康儿童钾需求以及低钾血症和高钾血症的饮食管理。描述了常见的含钾食物,并讨论了可纳入日常实践的调整钾摄入的方法。由于现有证据质量较差,因此进行了 Delphi 调查,以征求国际专家的共识。对于评级较低或基于意见的声明,必须根据治疗医生和营养师的临床判断,仔细考虑并针对个体患者的需求进行调整。PRNT 将定期审核和更新这些 CPR。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc8/8084813/cef33ca8652b/467_2021_4923_Fig1_HTML.jpg

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