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乌干达基鲁杜国家转诊医院维持性血液透析患者的饮食摄入、身体成分和微量营养素状况:一项横断面研究。

Dietary intake, body composition and micronutrient profile of patients on maintenance hemodialysis attending Kiruddu National Referral Hospital, Uganda: A cross sectional study.

机构信息

Department of Medical Physiology, Faculty of Health Sciences, Busitema University, Mbale, Uganda.

Department of Medical Physiology, College of Health Sciences, Makerere University, Kampala, Uganda.

出版信息

PLoS One. 2023 Oct 19;18(10):e0291813. doi: 10.1371/journal.pone.0291813. eCollection 2023.

Abstract

Patients on maintenance hemodialysis are at a great risk for altered nutritional status, characterized by protein energy wasting and micronutrient deficiency due to medication interactions and dietary restrictions. This study determined the dietary intake, micronutrient profile and body composition of patients on maintenance hemodialysis at Kiruddu National referral hospital (KNRH), Uganda. A cross sectional study was done among adult CKD patients on maintenance hemodialysis therapy at KNRH. Data concerning patients' demographics, clinical history and dietary intake was obtained using interactive and quantitative food frequency questionnaires. Body composition was obtained using the TANITA BC-351, Japan weighing Bathroom scale and anthropometric measurements using standard methods and procedures. Serum micronutrient profile assessment was done using the COBAS Auto analyzer. Data analysis was done using the SPSS software version 20. T-test was used to make comparisons and logistic regression analysis was done to check for any correlations. A P-value of < 0.05 was considered statistically significant. Among the 63 hemodialysis patients, 38% were female, with a median duration of hemodialysis of 12 months and the overall age range of patients was 31-40 years. Majority (92.1%) of the patients had hypertension. Carbohydrates like maize flour were highly consumed, in addition to eggs among the proteins on the daily basis. Fruits and vegetables were not highly consumed. Regarding body composition; 75% of the study participants had normal Body mass Index (BMI), the mean muscle mass was 51.94±8.68, body fat was 15.25±7.35, bone mass was 2.77±0.46 and body water was 62.04±9.06. Patients had deranged micronutrient levels especially for Vitamin D, Potassium and phosphorus. In conclusion, hemodialysis patients at KNRH, have altered nutritional status as evidenced by altered body weight for some patients and deranged micronutrient levels. We recommend that hemodialysis patients should be regularly assessed for nutritional status, appropriately treated and educated about their nutritional status.

摘要

接受维持性血液透析的患者存在营养状况改变的巨大风险,其特征为药物相互作用和饮食限制导致的蛋白质能量消耗和微量营养素缺乏。本研究旨在确定乌干达基鲁杜国家转诊医院(KNRH)接受维持性血液透析治疗的患者的饮食摄入、微量营养素状况和身体成分。在 KNRH 对接受维持性血液透析治疗的成年慢性肾脏病患者进行了横断面研究。使用交互式和定量食物频率问卷获取有关患者人口统计学、临床病史和饮食摄入的数据。使用 TANITA BC-351、日本称重浴室秤和标准方法和程序的人体测量学测量来获取身体成分。使用 COBAS Auto analyzer 进行血清微量营养素谱评估。使用 SPSS 软件版本 20 进行数据分析。使用 T 检验进行比较,使用逻辑回归分析检查任何相关性。P 值<0.05 被认为具有统计学意义。在 63 名血液透析患者中,38%为女性,血液透析中位时间为 12 个月,患者的总体年龄范围为 31-40 岁。大多数(92.1%)患者患有高血压。除了每天摄入蛋白质的鸡蛋外,还高度消费玉米粉等碳水化合物。水果和蔬菜的摄入量不高。关于身体成分;75%的研究参与者的体重指数(BMI)正常,平均肌肉量为 51.94±8.68,体脂肪为 15.25±7.35,骨量为 2.77±0.46,身体水分含量为 62.04±9.06。患者的微量营养素水平异常,特别是维生素 D、钾和磷。总之,KNRH 的血液透析患者的营养状况发生了改变,一些患者的体重发生了改变,微量营养素水平也发生了异常。我们建议定期评估血液透析患者的营养状况,对其进行适当的治疗,并对其营养状况进行教育。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef61/10586598/4bb48725e3a7/pone.0291813.g001.jpg

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