Department of General Surgery, Institute of Geriatric Medicine, Beijing Hospital, National Center of Gerontology, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
J Gastrointest Cancer. 2022 Jun;53(2):403-409. doi: 10.1007/s12029-021-00621-1. Epub 2021 Mar 17.
To investigate the impact of the COVID-19 pandemic on patients with colorectal cancer undergoing elective surgery.
The medical records of patients with colorectal cancer who underwent elective surgery in our department during the COVID-19 pandemic (February 1 to May 31, 2020) were collected and analyzed. We compared the clinical data with colorectal cancer during the same 4-month period in 2018 and 2019.
Sixty-seven patients with colorectal cancer underwent elective surgery during the COVID-19 pandemic. This was 66% of the number of patients that underwent the procedure during the same period in 2018 and 2019. During the COVID-19 pandemic, the proportion of patients without any digestive system symptoms decreased to 3% and severe clinical symptoms decreased by 20.9%. The proportion of right colon cancer decreased by 17.9%, while the proportion of rectal cancer increased by 52.2%, as compared with 2018 and 2019. The fraction of protective stoma was significantly higher than in 2018 (23.9% vs. 8.7%, p = 0.011). Compared with 2019, the average post-operative stay was significantly shorter than in 2018 (9.6 ± 3.7 vs. 12.1 ± 9.1, p = 0.015). Compared with 2019, the number of patients with perineural invasion (a feature of adverse prognosis) significantly increased (p = 0.009).
During the COVID-19 pandemic, the number of patients undergoing elective surgery for colorectal cancer was reduced. However, the tumor stage of patients did not change substantially. We suggest that the clinical diagnosis and treatment of colorectal cancer should strictly comply with national and professional standards.
研究 COVID-19 大流行对择期手术治疗的结直肠癌患者的影响。
收集并分析了 2020 年 2 月 1 日至 5 月 31 日期间在我科行择期手术的结直肠癌患者的病历资料。将其与 2018 年和 2019 年同期的结直肠癌临床资料进行比较。
COVID-19 大流行期间，67 例结直肠癌患者接受了择期手术，这一数字为 2018 年和 2019 年同期手术患者数量的 66%。在 COVID-19 大流行期间，无任何消化系统症状的患者比例降至 3%，严重临床症状减少了 20.9%。右半结肠癌的比例下降了 17.9%，而直肠癌的比例上升了 52.2%，与 2018 年和 2019 年相比。保护性造口的比例明显高于 2018 年（23.9%比 8.7%，p=0.011）。与 2019 年相比，2018 年患者术后平均住院时间明显缩短（9.6±3.7 比 12.1±9.1，p=0.015）。与 2019 年相比，神经侵犯患者数量（不良预后特征）显著增加（p=0.009）。
COVID-19 大流行期间，择期手术治疗结直肠癌的患者数量减少。然而，患者的肿瘤分期并没有发生实质性改变。我们建议，结直肠癌的临床诊断和治疗应严格遵守国家和专业标准。
