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输卵管妊娠:新冠疫情前和疫情期间的对比治疗管理。

Tubal ectopic pregnancy: comparative management between pre and Covid-19 pandemic periods.

机构信息

Universidade Federal de São Paulo Escola Paulista de Medicina Department of Obstetrics São PauloSP Brazil Department of Obstetrics, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Universidade de Uberaba Mário Palmério University Hospital Gynecology and Obstetrics Service UberabaMG Brazil Gynecology and Obstetrics Service, Mário Palmério University Hospital, Universidade de Uberaba, Uberaba, MG, Brazil.

出版信息

Rev Bras Ginecol Obstet. 2024 May 27;46. doi: 10.61622/rbgo/2024rbgo64. eCollection 2024.

Abstract

OBJECTIVE

To evaluate whether there were differences in the presentation of patients with tubal ectopic pregnancy (EP) during the first year of the COVID-19 pandemic.

METHODS

We performed a retrospective cohort study of all cases of tubal EP between March 2019 and March 2020 (pre-pandemic) and between March 2020 and March 2021 (pandemic). We compared between these two groups the risk factors, clinical characteristics, laboratory data, sonographic aspects, treatment applied and complications.

RESULTS

We had 150 EP diagnoses during the two years studied, of which 135 were tubal EP. Of these, 65 were included in the pre-pandemic and 70 in the pandemic period. The prevalence of lower abdominal pain was significantly higher in the pandemic compared to the pre-pandemic period (91.4% vs. 78.1%, p=0.031). There was no significant difference in shock index, initial beta-hCG level, hemoglobin level at diagnosis, days of menstrual delay, aspect of the adnexal mass, amount of free fluid on ultrasound, and intact or ruptured presentation between the groups. Expectant management was significantly higher during the pandemic period (40.0% vs. 18.5%, p=0.008), surgical management was lower during the pandemic period (47.1% vs. 67.7%, p=0.023), and number of days hospitalized was lower in the pandemic period (1.3 vs. 2.0 days, p=0.003).

CONCLUSION

We did not observe a significant difference in patient history, laboratory and ultrasound characteristics. Abdominal pain was more common during the pandemic period. Regarding treatment, we observed a significant increase in expectant and a decrease in surgical cases during the pandemic period.

摘要

目的

评估 COVID-19 大流行期间,输卵管妊娠(EP)患者的表现是否存在差异。

方法

我们对 2019 年 3 月至 2020 年 3 月(大流行前)和 2020 年 3 月至 2021 年 3 月(大流行期间)期间所有输卵管 EP 病例进行了回顾性队列研究。我们比较了这两组之间的危险因素、临床特征、实验室数据、超声表现、应用的治疗方法和并发症。

结果

我们在这两年的研究中诊断出 150 例 EP,其中 135 例为输卵管 EP。其中,65 例纳入大流行前组,70 例纳入大流行组。与大流行前组相比,大流行组下腹痛的发生率明显更高(91.4%比 78.1%,p=0.031)。休克指数、初始β-hCG 水平、诊断时血红蛋白水平、月经延迟天数、附件包块的表现、超声检查游离液量、完整或破裂的表现两组间无显著差异。大流行期间期待治疗的比例显著更高(40.0%比 18.5%,p=0.008),大流行期间手术治疗的比例较低(47.1%比 67.7%,p=0.023),大流行期间住院天数较少(1.3 天比 2.0 天,p=0.003)。

结论

我们没有观察到患者病史、实验室和超声特征有显著差异。大流行期间腹痛更常见。关于治疗,我们观察到大流行期间期待治疗的病例显著增加,手术治疗的病例减少。

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