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评估新冠疫情期间结肠癌护理的变化:罗马尼亚一家大学医院的四年分析

Assessing Changes in Colon Cancer Care during the COVID-19 Pandemic: A Four-Year Analysis at a Romanian University Hospital.

作者信息

Feier Catalin Vladut Ionut, Santoro Rebecca Rosa, Faur Alaviana Monique, Muntean Calin, Olariu Sorin

机构信息

First Discipline of Surgery, Department X-Surgery, "Victor Babes" University of Medicine and Pharmacy, 2 E. Murgu Sq., 300041 Timisoara, Romania.

First Surgery Clinic, "Pius Brinzeu" Clinical Emergency Hospital, 300723 Timisoara, Romania.

出版信息

J Clin Med. 2023 Oct 16;12(20):6558. doi: 10.3390/jcm12206558.

Abstract

This retrospective study investigates the impact of the COVID-19 pandemic on the surgical management of patients with colon cancer in a tertiary University Hospital in Timisoara, Romania. Data from 867 patients who underwent surgical interventions for this condition between 26 February 2019 and 25 February 2023 were meticulously analyzed to evaluate substantial shifts in the management and outcomes of these patients in comparison to the pre-pandemic era. The results reveal a substantial decrease in elective surgical procedures ( < 0.001) and a significant increase in emergency interventions ( < 0.001). However, postoperative mortality did not show significant variations. Of concern is the diagnosis of patients at more advanced stages of colon cancer, with a significant increase in Stage IV cases in the second year of the pandemic ( = 0.045). Average hospitalization durations recorded a significant decrease ( < 0.001) during the pandemic, and an inverse correlation between patient age and surgery duration was reported ( = 0.01, r = -0.088). This analysis provides a comprehensive perspective on how the pandemic has influenced the management of colon cancer, highlighting significant implications for the management and outcomes of these patients.

摘要

这项回顾性研究调查了新冠疫情对罗马尼亚蒂米什瓦拉市一所三级大学医院结肠癌患者手术治疗的影响。对2019年2月26日至2023年2月25日期间因该疾病接受手术干预的867例患者的数据进行了细致分析,以评估与疫情前时代相比,这些患者在治疗管理和治疗结果方面的重大变化。结果显示择期手术显著减少(<0.001),急诊手术显著增加(<0.001)。然而,术后死亡率没有显著变化。令人担忧的是结肠癌患者在更晚期阶段被诊断出来,在疫情的第二年,IV期病例显著增加(=0.045)。疫情期间平均住院时间显著缩短(<0.001),并且报告了患者年龄与手术时间之间呈负相关(=0.01,r=-0.088)。该分析全面展示了疫情如何影响结肠癌的治疗,突出了对这些患者的治疗管理和治疗结果的重大影响。

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