Centro de Desenvolvimento de Produto e Transferência de Tecnologia (CDP2T), Department of Mechanical Engineering, Escola Superior de Tecnologia de Setúbal, Instituto Politécnico de Setúbal, Setúbal, Portugal.
Centro de Desenvolvimento de Produto e Transferência de Tecnologia (CDP2T), Department of Mechanical Engineering, Escola Superior de Tecnologia de Setúbal, Instituto Politécnico de Setúbal, Setúbal, Portugal; Centro de Química Estrutural (CQE), Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal; Centro de investigação interdisciplinar Egas Moniz (CiiEM), Instituto Universitário Egas Moniz, Monte de Caparica, Portugal.
J Mech Behav Biomed Mater. 2021 Jun;118:104451. doi: 10.1016/j.jmbbm.2021.104451. Epub 2021 Mar 11.
The titanium implant/zirconia abutment interface can suffer failure upon mechanical and biological issues, ultimately leading to the loss of the artificial tooth. The study of the effect of the organic compounds present in saliva on the tribological behavior of these systems is of utmost importance to understand the failure mechanisms and better mimic the in vivo conditions. The aim of the present work is to evaluate the effect of the addition of albumin, urea, lysozyme and mucin to artificial saliva, on the triboactivity of Ti6Al4V/zirconia pair commonly used in dental implants and then, compare the results with those obtained with human saliva. The solutions' viscosity was measured and the adsorption of the different biomolecules to both Ti6Al4V and zirconia was accessed. Tribological tests were performed using Ti6Al4V balls sliding on zirconia plates inside of a corrosion cell. Friction and wear coefficients were determined, and the open circuit potential (OCP) was monitored during the tests. Also, the wear mechanisms were identified. The presence of mucin in the artificial lubricant led to the lowest wear coefficients. The main wear mechanism was abrasion, independently of the used lubricant. Adhesive wear was observed for the systems without mucin. Tribocorrosion activity and wear coefficient were lower in the presence of mucin. None of the studied artificial lubricants mimicked the effect of human saliva (HS) on the tribological behavior of the studied pair since this lubricant led to the lowest friction coefficient and highest corrosion activity.
钛种植体/氧化锆基台界面可能会因机械和生物问题而失效，最终导致人工牙齿脱落。研究唾液中存在的有机化合物对这些系统摩擦学行为的影响对于了解失效机制和更好地模拟体内条件至关重要。本工作的目的是评估在人工唾液中添加白蛋白、尿素、溶菌酶和粘蛋白对牙科种植体中常用的 Ti6Al4V/氧化锆对的摩擦活性的影响，然后将结果与人体唾液的结果进行比较。测量了溶液的粘度，并研究了不同生物分子在 Ti6Al4V 和氧化锆上的吸附情况。在腐蚀电池中，使用 Ti6Al4V 球在氧化锆板上滑动进行摩擦学测试。测定了摩擦和磨损系数，并在测试过程中监测开路电位 (OCP)。还确定了磨损机制。在人工润滑剂中存在粘蛋白会导致最低的磨损系数。主要磨损机制是磨料磨损，而与使用的润滑剂无关。在没有粘蛋白的系统中观察到粘着磨损。在粘蛋白存在的情况下，摩擦腐蚀活性和磨损系数较低。在所研究的人工润滑剂中，没有一种能模拟人唾液 (HS) 对所研究配对物摩擦学行为的影响，因为这种润滑剂导致了最低的摩擦系数和最高的腐蚀活性。
