诱导多能干细胞（iPSC）系（ZZUNEUi009-A）取自健康女性个体。
Induced pluripotent stem cell (iPSC) line (ZZUNEUi009-A) from a healthy female individual.
机构信息
Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Henan Key Laboratory of Hereditary Cardiovascular Diseases, Zhengzhou 450052, China.
Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Henan Key Laboratory of Hereditary Cardiovascular Diseases, Zhengzhou 450052, China; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Centre for Cardiovascular Diseases, No. 2 Beijing Anzhen Road, Chaoyang District, Beijing 100029, China.
出版信息
Stem Cell Res. 2021 May;53:102275. doi: 10.1016/j.scr.2021.102275. Epub 2021 Mar 3.
Induced pluripotent stem cells (iPSCs) can be used to generate different types of somatic cells in vitro and are a useful tool for investigating drug and disease mechanisms. Here, we generated human induced pluripotent stem cell (iPSC) line ZZUNEUi009-A from an apparently healthy 28-year-old female by reprogramming peripheral blood mononuclear cells with non-integrating vector. The generated iPSCs was pluripotent, maintained a stable karyotype, and could generate the three layers (ectoderm, mesoderm, and endoderm) in vitro.
诱导多能干细胞（iPSC）可用于体外生成不同类型的体细胞，是研究药物和疾病机制的有用工具。本研究通过非整合载体重编程外周血单个核细胞，从一位看似健康的 28 岁女性获得了人诱导多能干细胞（iPSC）系 ZZUNEUi009-A。该 iPSC 具有多能性，保持稳定的核型，并可在体外生成三胚层（外胚层、中胚层和内胚层）。
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