Guo L W, Zhang S K, Liu S Z, Zheng L Y, Yu J, Chen Q, Cao X Q, Sun X B, Zhang J G
Henan Office for Cancer Control and Research, Henan Engineering Research Center of Cancer Prevention and Control, Henan International Joint Laboratory of Cancer Prevention, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou 450008, China.
Endoscopic Diagnosis and Treatment Center, Henan Cancer Hospital/The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2021 Mar 6;55(3):353-358. doi: 10.3760/cma.j.cn112150-20200304-00242.
To evaluate the compliance of colonoscopy screening and the detection rate of colorectal lesions with colonoscopy in urban areas of Henan province from 2013 to 2019. The study objects were derived from the Cancer Screening Program in Urban Henan Province, China. From October 2013 to October 2019, 282 377 residents, who had lived in the local area for more than three years, were recruited from Zhengzhou, Zhumadian, Anyang, Luoyang, Nanyang, Jiaozuo, Puyang and Xinxiang. The cancer risk assessment questionnaire was used to collect basic demographic characteristics, eating habits, living environment and habits, psychology and emotions, past disease history and family history of cancer, and women's physiological and reproductive history. The cancer risk assessment model was used for evaluating the risk of colorectal cancer. The data related to colonoscopy screening was obtained from the participating hospitals. Chi-square test was used to analyze the compliance rate among different groups. The 282 377 subjects were (55.26±8.68) years old, of which 44.80% (126 505) were males, and 67.63% (190 694) had junior/senior/tertiary education background. A total of 39 834 (14.11%) subjects were assessed to be at high risk for colorectal cancer, of which 7 454 took the following colonoscopy screening, yielding a participation rate of 18.71%. The screening rate was higher in those aged 50 to 54 (20.42%) and 55 to 59 (20.43%) years, and lowest in those aged 70 years and older (12.30%) (<0.001). A total of 17 colorectal cancer cases were detected, with a detection rate of 0.23% (17/7 454). Colonoscopy as a means of screening for colorectal cancer is helpful for early detection of colorectal lesions, but the participation rate is poor.
评估2013年至2019年河南省城市地区结肠镜检查筛查的依从性及结肠镜检查对结直肠病变的检出率。研究对象来源于中国河南省城市癌症筛查项目。2013年10月至2019年10月，从郑州、驻马店、安阳、洛阳、南阳、焦作、濮阳和新乡招募了282377名在当地居住三年以上的居民。采用癌症风险评估问卷收集基本人口学特征、饮食习惯、生活环境与习惯、心理与情绪、既往病史和癌症家族史以及女性生理和生殖史。采用癌症风险评估模型评估结直肠癌风险。结肠镜检查筛查相关数据来自参与研究的医院。采用卡方检验分析不同组间的依从率。282377名受试者年龄为（55.26±8.68）岁，其中男性占44.80%（126505人），初中/高中/大专及以上学历者占67.63%（190694人）。共有39834名（14.11%）受试者被评估为结直肠癌高风险人群，其中7454人接受了后续结肠镜检查筛查，参与率为18.71%。50至54岁（20.42%）和55至59岁（20.43%）人群的筛查率较高，70岁及以上人群的筛查率最低（12.30%）（P<0.001）。共检测出17例结直肠癌病例，检出率为0.23%（17/7454）。结肠镜检查作为结直肠癌的筛查手段有助于早期发现结直肠病变，但参与率较低。
