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质谱仪假象:两种挥发性麻醉剂的同时检测

Mass spectrometer artifact: simultaneous detection of two volatile anesthetics.

作者信息

Dhruva S A, Dhamee M S, Hensler T

机构信息

Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI 53226.

出版信息

J Clin Monit. 1988 Apr;4(2):122-4. doi: 10.1007/BF01641814.

DOI:10.1007/BF01641814
PMID:3373252
Abstract

In several cases, a mass spectrometer indicated that both enflurane and isoflurane were being detected while only isoflurane was in use. The concentration of expired enflurane reported was always higher than the inspired concentration, but never exceeded 0.66% regardless of the concentration of isoflurane. Such mass spectrometer readings may be evidence of vaporizer contamination or malfunction of the vaporizer; however, in this case, the mass spectrometer was found to be out of calibration. Because mass spectrometers are recent additions to clinical equipment, procedures for routine calibration and maintenance must be carefully scrutinized and evaluated.

摘要

在几起案例中,一台质谱仪显示,虽然仅使用了异氟烷,但同时检测到了恩氟烷和异氟烷。报告的呼出恩氟烷浓度始终高于吸入浓度,但无论异氟烷浓度如何,该浓度从未超过0.66%。此类质谱仪读数可能是蒸发器污染或蒸发器故障的证据;然而,在本案例中,发现质谱仪校准不当。由于质谱仪是临床设备中的新成员,必须仔细审查和评估常规校准和维护程序。

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Mass spectrometer artifact: simultaneous detection of two volatile anesthetics.质谱仪假象:两种挥发性麻醉剂的同时检测
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引用本文的文献

1
Erroneous mass spectrometer data caused by a faulty patient sampling tube: case report and laboratory study.患者采样管故障导致质谱仪数据错误:病例报告与实验室研究
J Clin Monit. 1991 Oct;7(4):313-9. doi: 10.1007/BF01619352.

本文引用的文献

1
A gas mixer for computer calibration of an anesthetic mass spectrometer.
J Clin Monit. 1986 Oct;2(4):223-9. doi: 10.1007/BF02851169.
2
Recognition of mixed anesthetic agents by mass spectrometer during anesthesia.麻醉期间通过质谱仪识别混合麻醉剂。
J Clin Monit. 1986 Apr;2(2):121-4. doi: 10.1007/BF01637679.