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Induction of Epithelial-mesenchymal Transition in MDCK II Cells.诱导MDCK II细胞发生上皮-间质转化
Bio Protoc. 2021 Feb 5;11(3):e3903. doi: 10.21769/BioProtoc.3903.
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High-throughput mRNA and miRNA profiling of epithelial-mesenchymal transition in MDCK cells.MDCK细胞上皮-间质转化的高通量mRNA和miRNA分析
BMC Genomics. 2015 Nov 16;16:944. doi: 10.1186/s12864-015-2036-9.
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P73 tumor suppressor and its targets, p21 and PUMA, are required for madin-darby canine kidney cell morphogenesis by maintaining an appropriate level of epithelial to mesenchymal transition.P73肿瘤抑制因子及其靶点p21和PUMA通过维持上皮向间充质转化的适当水平，对马-达二氏犬肾细胞形态发生是必需的。
Oncotarget. 2015 Jun 10;6(16):13994-4004. doi: 10.18632/oncotarget.4374.
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Oncogenic H-ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition.致癌性 H-ras 重编程 Madin-Darby 犬肾 (MDCK) 细胞衍生的细胞外体蛋白，随后发生上皮-间充质转化。
Mol Cell Proteomics. 2013 Aug;12(8):2148-59. doi: 10.1074/mcp.M112.027086. Epub 2013 May 3.
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Transglutaminase-2, RNA-binding proteins and mitochondrial proteins selectively traffic to MDCK cell-derived microvesicles following H-Ras-induced epithelial-mesenchymal transition.转谷氨酰胺酶-2、RNA 结合蛋白和线粒体蛋白在 H-Ras 诱导的上皮-间充质转化后选择性地转运到 MDCK 细胞衍生的微泡中。
Proteomics. 2021 Jul;21(13-14):e2000221. doi: 10.1002/pmic.202000221. Epub 2021 Mar 19.
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Regulation of Epithelial-to-Mesenchymal Transition Using Biomimetic Fibrous Scaffolds.使用仿生纤维支架调控上皮-间充质转化
ACS Appl Mater Interfaces. 2016 Jul 20;8(28):17915-26. doi: 10.1021/acsami.6b05646. Epub 2016 Jul 5.
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The ectopic expression of Snail in MDBK cells does not induce epithelial-mesenchymal transition.Snail在MDBK细胞中的异位表达不会诱导上皮-间质转化。
Int J Mol Med. 2015 Jul;36(1):166-72. doi: 10.3892/ijmm.2015.2215. Epub 2015 May 19.
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SLC35A2 Deficiency Promotes an Epithelial-to-Mesenchymal Transition-like Phenotype in Madin-Darby Canine Kidney Cells.SLC35A2 缺乏促进 Madin-Darby 犬肾细胞发生上皮间质转化样表型。
Cells. 2022 Jul 23;11(15):2273. doi: 10.3390/cells11152273.
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Galectin-8 induces partial epithelial-mesenchymal transition with invasive tumorigenic capabilities involving a FAK/EGFR/proteasome pathway in Madin-Darby canine kidney cells.半乳糖凝集素-8 诱导具有侵袭性肿瘤发生能力的部分上皮间质转化，涉及 Madin-Darby 犬肾细胞中的 FAK/EGFR/蛋白酶体通路。
Mol Biol Cell. 2018 Mar 1;29(5):557-574. doi: 10.1091/mbc.E16-05-0301. Epub 2018 Jan 3.
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Alpha1-Antitrypsin Attenuates Renal Fibrosis by Inhibiting TGF-β1-Induced Epithelial Mesenchymal Transition.α1-抗胰蛋白酶通过抑制转化生长因子-β1诱导的上皮-间质转化减轻肾纤维化。
PLoS One. 2016 Sep 8;11(9):e0162186. doi: 10.1371/journal.pone.0162186. eCollection 2016.
引用本文的文献
1
Emergence of multiple collective motility modes in a physical model of cell chains.细胞链物理模型中多种集体运动模式的出现。
NPJ Syst Biol Appl. 2025 May 22;11(1):52. doi: 10.1038/s41540-025-00529-7.
2
Calcium-binding Cab45 regulates the polarized apical secretion of soluble proteins in epithelial cells.钙结合蛋白 Cab45 调控上皮细胞中可溶性蛋白的极化顶端分泌。
Mol Biol Cell. 2023 Jul 1;34(8):br12. doi: 10.1091/mbc.E22-12-0549. Epub 2023 May 10.
本文引用的文献
1
Cellular Plasticity in Cancer.癌症中的细胞可塑性。
Cancer Discov. 2019 Jul;9(7):837-851. doi: 10.1158/2159-8290.CD-19-0015. Epub 2019 Apr 16.
2
New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer.上皮-间质转化的机制新见解及其对癌症的影响。
Nat Rev Mol Cell Biol. 2019 Feb;20(2):69-84. doi: 10.1038/s41580-018-0080-4.
3
Endocytic turnover of Rab8 controls cell polarization.Rab8的内吞周转控制细胞极化。
J Cell Sci. 2017 Mar 15;130(6):1147-1157. doi: 10.1242/jcs.195420. Epub 2017 Jan 30.
4
Differential sensitivity of epithelial cells to extracellular matrix in polarity establishment.上皮细胞在极性建立过程中对细胞外基质的差异敏感性。
PLoS One. 2014 Nov 13;9(11):e112922. doi: 10.1371/journal.pone.0112922. eCollection 2014.
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RANKL promotes migration and invasion of hepatocellular carcinoma cells via NF-κB-mediated epithelial-mesenchymal transition.核因子κB受体活化因子配体（RANKL）通过核因子κB（NF-κB）介导的上皮-间质转化促进肝癌细胞的迁移和侵袭。
PLoS One. 2014 Sep 30;9(9):e108507. doi: 10.1371/journal.pone.0108507. eCollection 2014.
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Signaling mechanisms of the epithelial-mesenchymal transition.上皮-间质转化的信号传导机制
Sci Signal. 2014 Sep 23;7(344):re8. doi: 10.1126/scisignal.2005189.
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HGF induces epithelial-to-mesenchymal transition by modulating the mammalian hippo/MST2 and ISG15 pathways.HGF 通过调节哺乳动物 Hippo/MST2 和 ISG15 通路诱导上皮间质转化。
J Proteome Res. 2014 Jun 6;13(6):2874-86. doi: 10.1021/pr5000285. Epub 2014 May 5.
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Epithelial-mesenchymal transition induced by TNF-α requires NF-κB-mediated transcriptional upregulation of Twist1.TNF-α 诱导的上皮-间充质转化需要 NF-κB 介导的 Twist1 转录上调。
Cancer Res. 2012 Mar 1;72(5):1290-300. doi: 10.1158/0008-5472.CAN-11-3123. Epub 2012 Jan 17.
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The MDCK variety pack: choosing the right strain.MDCK 多种菌株组合：选择合适的菌株。
BMC Cell Biol. 2011 Oct 7;12:43. doi: 10.1186/1471-2121-12-43.
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IL-6 promotes head and neck tumor metastasis by inducing epithelial-mesenchymal transition via the JAK-STAT3-SNAIL signaling pathway.白细胞介素 6 通过 JAK-STAT3-SNAIL 信号通路诱导上皮间质转化促进头颈部肿瘤转移。
Mol Cancer Res. 2011 Dec;9(12):1658-67. doi: 10.1158/1541-7786.MCR-11-0271. Epub 2011 Oct 5.
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