• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

澳大利亚 1 级创伤中心急诊科即时 ROTEM 检测的引入及其对血液制品使用的影响。

Introduction of point-of-care ROTEM testing in the emergency department of an Australian level 1 trauma centre and its effect on blood product use.

机构信息

Trauma Service, Royal Adelaide Hospital, Adelaide, South Australia, Australia.

Transfusion Medicine, SA Department for Health and Wellbeing, Flinders Medical Centre and Royal Adelaide Hospital, Adelaide, South Australia, Australia.

出版信息

Emerg Med Australas. 2021 Oct;33(5):893-899. doi: 10.1111/1742-6723.13767. Epub 2021 Mar 17.

DOI:10.1111/1742-6723.13767
PMID:33733606
Abstract

OBJECTIVE

To assess whether the introduction of point-of-care rotational thromboelastometry (ROTEM) analysis influences blood product transfusion and coagulation management in a modern Australian level 1 trauma centre.

METHODS

Retrospective blood transfusion data collection from all level 1 trauma patients with an Injury Severity Score (ISS) >12 presenting to the Royal Adelaide Hospital in 2016 and 2018. Evaluation of changes in blood product administration with the addition of point-of-care viscoelastic testing in the ED in 2018.

RESULTS

A total of 774 patients were analysed with 380 in 2016 and 394 in 2018. Almost a quarter of all 2018 trauma patients (93/394) had ROTEM performed within 24 h of ED arrival, 42% of these having an ISS >25. There was a significant increase in the number of patients receiving cryoprecipitate following the introduction of ROTEM (P = 0.01). In those receiving cryoprecipitate, there was a significant reduction in subsequent platelet and fresh frozen plasma use (P < 0.001). Overall, there was a reduction in expenditure on red cells, platelets and fresh frozen plasma from 2016 to 2018.

CONCLUSION

Point-of-care ROTEM was performed in a small proportion of patients, mainly those with a higher ISS. ROTEM introduction in the ED altered blood product transfusion practices for major trauma patients with an ISS >12, leading to a potentially safer transfusion strategy and cost savings for key blood products.

摘要

目的

评估即时凝血弹性成像(ROTEM)分析在澳大利亚 1 级创伤中心的引入是否影响血液制品的输注和凝血管理。

方法

对 2016 年和 2018 年所有创伤严重程度评分(ISS)>12 级的 1 级创伤患者进行回顾性输血数据收集。评估在 ED 中添加即时凝血弹性成像后血液制品管理的变化。

结果

共分析了 774 例患者,其中 2016 年 380 例,2018 年 394 例。2018 年几乎四分之一的创伤患者(93/394)在 ED 到达后 24 小时内进行了 ROTEM,其中 42%的 ISS >25。在引入 ROTEM 后,接受冷沉淀的患者数量显著增加(P=0.01)。在接受冷沉淀的患者中,随后血小板和新鲜冷冻血浆的使用显著减少(P<0.001)。总体而言,2016 年至 2018 年红细胞、血小板和新鲜冷冻血浆的支出减少。

结论

即时 ROTEM 仅在一小部分患者中进行,主要是那些 ISS 较高的患者。ED 中 ROTEM 的引入改变了 ISS >12 的严重创伤患者的血液制品输注实践,导致潜在更安全的输血策略和关键血液制品的成本节约。

相似文献

1
Introduction of point-of-care ROTEM testing in the emergency department of an Australian level 1 trauma centre and its effect on blood product use.澳大利亚 1 级创伤中心急诊科即时 ROTEM 检测的引入及其对血液制品使用的影响。
Emerg Med Australas. 2021 Oct;33(5):893-899. doi: 10.1111/1742-6723.13767. Epub 2021 Mar 17.
2
Viscoelastic point-of-care testing to assist with the diagnosis, management and monitoring of haemostasis: a systematic review and cost-effectiveness analysis.用于辅助止血诊断、管理和监测的即时粘弹性检测:系统评价与成本效益分析
Health Technol Assess. 2015 Jul;19(58):1-228, v-vi. doi: 10.3310/hta19580.
3
Rotational thromboelastometry in children presenting to an Australian major trauma centre: A retrospective cohort study.澳大利亚一家大型创伤中心就诊患儿的旋转血栓弹性描记术:一项回顾性队列研究。
Emerg Med Australas. 2022 Aug;34(4):590-598. doi: 10.1111/1742-6723.13939. Epub 2022 Feb 24.
4
Guided blood transfusion of trauma patients with rotational thromboelastometry: a single-center cohort study.运用旋转血栓弹力描记术指导创伤患者输血:一项单中心队列研究。
World J Emerg Surg. 2023 Jul 1;18(1):40. doi: 10.1186/s13017-023-00508-5.
5
Utility of rotational thromboelastometry in the management of massive haemorrhage at a regional Australian hospital.澳大利亚某地区医院在大出血管理中应用旋转血栓弹性测定术的效用。
Transfus Med. 2024 Feb;34(1):54-60. doi: 10.1111/tme.13018. Epub 2023 Nov 29.
6
Rotational thromboelastometry-guided transfusion during lumbar pedicle subtraction osteotomy for adult spinal deformity: preliminary findings from a matched cohort study.旋转血栓弹性描记术引导下的腰椎弓根截骨术治疗成人脊柱畸形的输血:一项匹配队列研究的初步发现。
Neurosurg Focus. 2019 Apr 1;46(4):E17. doi: 10.3171/2019.1.FOCUS18572.
7
Rotational thromboelastometry significantly optimizes transfusion practices for damage control resuscitation in combat casualties.旋转血栓弹力图显著优化了战斗伤员损伤控制复苏的输血方案。
J Trauma Acute Care Surg. 2017 Sep;83(3):373-380. doi: 10.1097/TA.0000000000001568.
8
Rotational Thromboelastometry or Conventional Coagulation Tests in Liver Transplantation: Comparing Blood Loss, Transfusions, and Cost.肝移植中旋转血栓弹力图或传统凝血试验:比较失血量、输血情况和成本
Ann Hepatol. 2017;16(6):916-923. doi: 10.5604/01.3001.0010.5283.
9
Rotational thromboelastometry-guided blood product management in major spine surgery.旋转血栓弹性描记术指导下的大型脊柱手术中血液制品管理。
J Neurosurg Spine. 2015 Aug;23(2):239-49. doi: 10.3171/2014.12.SPINE14620. Epub 2015 May 22.
10
Rotational ThromboElastometry-guided blood component administration versus standard of care in patients with Cirrhosis and coagulopathy undergoing Invasive ProcEdures (RECIPE): study protocol for a randomised controlled trial.旋转血栓弹性测定引导下的血液成分输注与肝硬化合并凝血障碍患者接受侵入性操作时的常规护理对比(RECIPE):一项随机对照试验的研究方案。
Trials. 2023 Aug 11;24(1):516. doi: 10.1186/s13063-023-07552-1.

引用本文的文献

1
The influence of rotational thromboelastometry (ROTEM) on operating room and intensive care transfusion practices in major trauma bleeding: a prospective cohort study with historical control.旋转血栓弹力图(ROTEM)对严重创伤出血患者手术室及重症监护输血治疗的影响:一项采用历史对照的前瞻性队列研究
Perioper Med (Lond). 2025 Jul 21;14(1):75. doi: 10.1186/s13741-025-00562-4.
2
Revolutionizing trauma care: advancing coagulation management and damage control anesthesia.革新创伤护理:推进凝血管理与损伤控制麻醉。
Anesth Pain Med (Seoul). 2024 Apr;19(2):73-84. doi: 10.17085/apm.24038. Epub 2024 Apr 30.
3
Update on the pathophysiology and management of acute trauma hemorrhage and trauma-induced coagulopathy based upon viscoelastic testing.
基于粘弹性检测的急性创伤出血及创伤性凝血病的病理生理学与治疗进展
Clin Exp Emerg Med. 2024 Sep;11(3):259-267. doi: 10.15441/ceem.24.202. Epub 2024 Mar 15.
4
[Viscoelasticity-based point of care coagulation diagnostics in the context of resuscitation room management of severely injured and bleeding trauma patients : Diagnostics and treatment of trauma-induced coagulopathy].[在严重受伤和出血性创伤患者复苏室管理背景下基于粘弹性的即时凝血诊断:创伤性凝血病的诊断与治疗]
Unfallchirurgie (Heidelb). 2023 Jul;126(7):542-551. doi: 10.1007/s00113-023-01300-5. Epub 2023 Mar 28.
5
The European guideline on management of major bleeding and coagulopathy following trauma: sixth edition.《欧洲创伤后大出血及凝血功能障碍管理指南》第六版
Crit Care. 2023 Mar 1;27(1):80. doi: 10.1186/s13054-023-04327-7.
6
Letter to the Editor Regarding "Viscoelastic Hemostatic Assays and Outcomes in Traumatic Brain Injury: A Systematic Literature Review".致编辑的信:关于“创伤性脑损伤中的粘弹性止血检测与结果:系统文献综述”
World Neurosurg. 2022 Oct;166:291-293. doi: 10.1016/j.wneu.2022.04.040.
7
Evaluation of the Effect of Storage Time on ROTEM S Parameters in Healthy and Ill Dogs.储存时间对健康犬和患病犬ROTEM S参数影响的评估
Animals (Basel). 2022 Aug 7;12(15):1996. doi: 10.3390/ani12151996.