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澳大利亚 1 级创伤中心急诊科即时 ROTEM 检测的引入及其对血液制品使用的影响。

Introduction of point-of-care ROTEM testing in the emergency department of an Australian level 1 trauma centre and its effect on blood product use.

机构信息

Trauma Service, Royal Adelaide Hospital, Adelaide, South Australia, Australia.

Transfusion Medicine, SA Department for Health and Wellbeing, Flinders Medical Centre and Royal Adelaide Hospital, Adelaide, South Australia, Australia.

出版信息

Emerg Med Australas. 2021 Oct;33(5):893-899. doi: 10.1111/1742-6723.13767. Epub 2021 Mar 17.

Abstract

OBJECTIVE

To assess whether the introduction of point-of-care rotational thromboelastometry (ROTEM) analysis influences blood product transfusion and coagulation management in a modern Australian level 1 trauma centre.

METHODS

Retrospective blood transfusion data collection from all level 1 trauma patients with an Injury Severity Score (ISS) >12 presenting to the Royal Adelaide Hospital in 2016 and 2018. Evaluation of changes in blood product administration with the addition of point-of-care viscoelastic testing in the ED in 2018.

RESULTS

A total of 774 patients were analysed with 380 in 2016 and 394 in 2018. Almost a quarter of all 2018 trauma patients (93/394) had ROTEM performed within 24 h of ED arrival, 42% of these having an ISS >25. There was a significant increase in the number of patients receiving cryoprecipitate following the introduction of ROTEM (P = 0.01). In those receiving cryoprecipitate, there was a significant reduction in subsequent platelet and fresh frozen plasma use (P < 0.001). Overall, there was a reduction in expenditure on red cells, platelets and fresh frozen plasma from 2016 to 2018.

CONCLUSION

Point-of-care ROTEM was performed in a small proportion of patients, mainly those with a higher ISS. ROTEM introduction in the ED altered blood product transfusion practices for major trauma patients with an ISS >12, leading to a potentially safer transfusion strategy and cost savings for key blood products.

摘要

目的

评估即时凝血弹性成像(ROTEM)分析在澳大利亚 1 级创伤中心的引入是否影响血液制品的输注和凝血管理。

方法

对 2016 年和 2018 年所有创伤严重程度评分(ISS)>12 级的 1 级创伤患者进行回顾性输血数据收集。评估在 ED 中添加即时凝血弹性成像后血液制品管理的变化。

结果

共分析了 774 例患者,其中 2016 年 380 例,2018 年 394 例。2018 年几乎四分之一的创伤患者(93/394)在 ED 到达后 24 小时内进行了 ROTEM,其中 42%的 ISS >25。在引入 ROTEM 后,接受冷沉淀的患者数量显著增加(P=0.01)。在接受冷沉淀的患者中,随后血小板和新鲜冷冻血浆的使用显著减少(P<0.001)。总体而言,2016 年至 2018 年红细胞、血小板和新鲜冷冻血浆的支出减少。

结论

即时 ROTEM 仅在一小部分患者中进行,主要是那些 ISS 较高的患者。ED 中 ROTEM 的引入改变了 ISS >12 的严重创伤患者的血液制品输注实践,导致潜在更安全的输血策略和关键血液制品的成本节约。

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