SUNY Upstate Medical University, Syracuse, NY, USA.
J Investig Med High Impact Case Rep. 2021 Jan-Dec;9:23247096211001659. doi: 10.1177/23247096211001659.
We report the case of a 71-year-old female who was incidentally found to have nonoliguric acute kidney injury on a routine workup for new-onset visual hallucination. Further history revealed inadvertent usage of nitrofurantoin for 3 months for an anticipated urological procedure. Renal biopsy demonstrated acute granulomatous interstitial nephritis. The renal function significantly improved following discontinuation of nitrofurantoin and corticosteroid administration. We highlight a rare association of nitrofurantoin with acute granulomatous interstitial nephritis through this case report.
我们报告了一例 71 岁女性的病例,她在因新发视觉幻觉进行常规检查时意外发现非少尿性急性肾损伤。进一步的病史显示,她曾在 3 个月前因预期的泌尿科手术而意外使用了呋喃妥因。肾活检显示急性肉芽肿性间质性肾炎。停用呋喃妥因和给予皮质类固醇后,肾功能显著改善。通过本病例报告,我们强调了呋喃妥因与急性肉芽肿性间质性肾炎之间的罕见关联。