使用过硫酸钠氧化酯化法制备六氟异丙酯。

Preparation of hexafluoroisopropyl esters by oxidative esterification of aldehydes using sodium persulfate.

机构信息

Department of Chemistry, University of Connecticut, 55 North Eagleville Road, Storrs, Connecticut 06269, USA.

出版信息

Org Biomol Chem. 2021 Apr 7;19(13):2986-2990. doi: 10.1039/d1ob00251a. Epub 2021 Mar 18.

Abstract

A simple, metal-free route for the oxidative esterification of aldehydes to yield hexafluoroisopropyl esters is reported. The methodology employs sodium persulfate and a catalytic quantity of a nitroxide and is applicable to aromatic, heteroaromatic, and aliphatic aldehydes.

摘要

本文报道了一种简单的、无金属的醛氧化酯化方法，可得到六氟异丙酯。该方法使用过硫酸钠和催化量的氮氧自由基，并适用于芳香醛、杂环醛和脂肪醛。