Heather P. McLaughlin is with the Division of Preparedness and Emerging Infections, Centers for Disease Control and Prevention, Atlanta, GA. Brian C. Hiatt, Denny Russell, Ailyn C. Perez-Osorio, Sung W. Choi, and Romesh K. Gautom are with the Washington State Public Health Laboratories, Washington State Department of Health, Shoreline. Christina M. Carlson and Jesica R. Jacobs are with the Laboratory Leadership Service, Centers for Disease Control and Prevention. Michelle L. Holshue is a Career Epidemiology Field Officer, Centers for Disease Control and Prevention.
Note. The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. Use of trade names is for identification only and does not imply endorsement by the Centers for Disease Control and Prevention.
Am J Public Health. 2021 May;111(5):867-875. doi: 10.2105/AJPH.2021.306212. Epub 2021 Mar 18.
Laboratory diagnostics play an essential role in pandemic preparedness. In January 2020, the first US case of COVID-19 was confirmed in Washington State. At the same time, the Washington State Public Health Laboratory (WA PHL) was in the process of building upon and initiating innovative preparedness activities to strengthen laboratory testing capabilities, operations, and logistics. The response efforts of WA PHL, in conjunction with the Centers for Disease Control and Prevention, to the COVID-19 outbreak in Washington are described herein-from the initial detection of severe acute respiratory syndrome coronavirus 2 through the subsequent 2 months.Factors that contributed to an effective laboratory response are described, including preparing early to establish testing capacity, instituting dynamic workforce solutions, advancing information management systems, refining laboratory operations, and leveraging laboratory partnerships. We also report on the challenges faced, successful steps taken, and lessons learned by WA PHL to respond to COVID-19.The actions taken by WA PHL to mount an effective public health response may be useful for US laboratories as they continue to respond to the COVID-19 pandemic and may help inform current and future laboratory pandemic preparedness activities.
实验室诊断在大流行准备中起着至关重要的作用。2020 年 1 月,美国首例 COVID-19 病例在华盛顿州得到确认。与此同时,华盛顿州公共卫生实验室(WA PHL)正在建立和启动创新的准备活动,以加强实验室检测能力、运营和后勤。本文描述了 WA PHL 与疾病预防控制中心一起应对华盛顿 COVID-19 疫情的反应工作——从最初检测到严重急性呼吸综合征冠状病毒 2 到随后的 2 个月。描述了有助于有效实验室反应的因素,包括及早准备建立检测能力、实施动态劳动力解决方案、推进信息管理系统、完善实验室操作以及利用实验室伙伴关系。我们还报告了 WA PHL 在应对 COVID-19 时面临的挑战、采取的成功措施和吸取的经验教训。WA PHL 为实施有效公共卫生应对措施而采取的行动可能对美国实验室有用,因为它们继续应对 COVID-19 大流行,并可能有助于为当前和未来的实验室大流行准备活动提供信息。