Thayer School of Engineering at Dartmouth, Geisel School of Medicine at Dartmouth, Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.
Med Phys. 2021 Jun;48(6):3151-3159. doi: 10.1002/mp.14849. Epub 2021 Apr 7.
The field of medical physics has struggled with the role of research in recent years, as professional interests have dominated its growth toward clinical service. This article focuses on the subset of medical physics programs within academic medical centers and how a refocused academic mission within these centers should drive and support Discovery and Invention with Ventures and Engineering for Research Translation (DIVERT). A roadmap to a DIVERT-based scholarly research program is discussed here around the core building blocks of: (a) creativity in research and team building, (b) improved quality metrics to assess activity, (c) strategic partnerships and spinoff directions that extend capabilities, and (d) future directions driven by faculty-led initiatives. Within academia, it is the unique discoveries and inventions of faculty that lead to their recognition as scholars, and leads to financial support for their research programs and reconition of their intellectual contributions. Innovation must also be coupled to translation to demonstrate outcome successes. These ingredients are critical for research funding, and the two-decade growth in biomedical engineering research funding is an illustration of this, where technology invention has been the goal. This record can be contrasted with flat funding within radiation oncology and radiology, where a growing fraction of research is more procedure-based. However, some centers are leading the change of the definition of medical physics, by the inclusion or assimilation of researchers in fields such as biomedical engineering, machine learning, or data science, thereby widening the scope for new discoveries and inventions. New approaches to the assessment of research quality can help realize this model, revisiting the measures of success and impact. While research partnerships with large industry are productive, newer efforts that foster enterprise startups are changing how institutions see the benefits of the connection between academic innovation and affiliated startup company formation. This innovation-to-enterprise focus can help to cultivate a broader bandwidth of donor-to-investor networks. There are many predictions on future directions in medical physics, yet the actual inventive and discovery steps come from individual research faculty creativity. All success through a DIVERT model requires that faculty-led initiatives span the gap from invention to translation, with support from institutional leadership at all steps in the process. Institutional investment in faculty through endowments or clinical revenues will likely need to increase in the coming years due to the relative decreasing size of grants. Yet, radiology and radiation oncology are both high-revenue, translational fields, with the capacity to synergistically support clinical and research operations through large infrastructures that are mutually beneficial. These roadmap principles can provide a pathway for committed academic medical physics programs in scholarly leadership that will preserve medical physics as an active part of university academics.
近年来,医学物理学领域一直在努力探索其研究角色,因为专业兴趣主导了其向临床服务的发展。本文聚焦于学术医疗中心内的医学物理学项目子集,以及如何重新聚焦这些中心内的学术使命,以推动和支持发现和发明,实现风险投资和工程研究转化(DIVERT)。本文围绕以下核心组成部分讨论了基于 DIVERT 的学术研究计划的路线图:(a)研究和团队建设中的创造力,(b)提高质量指标以评估活动,(c)扩展能力的战略伙伴关系和衍生方向,以及(d)由教师主导的倡议驱动的未来方向。在学术界,正是教师的独特发现和发明使他们成为学者,并为他们的研究计划提供资金支持,并承认他们的知识贡献。创新也必须与转化相结合,以展示成果成功。这些要素对于研究资金至关重要,生物医学工程研究资金在过去二十年的增长就是一个例证,其中技术发明是目标。这一记录与放射肿瘤学和放射学的资金持平形成鲜明对比,在这些领域,越来越多的研究更侧重于程序。然而,一些中心正在通过纳入或吸收生物医学工程、机器学习或数据科学等领域的研究人员来引领医学物理学定义的变革,从而为新发现和发明拓宽了范围。新的研究质量评估方法可以帮助实现这一模式,重新审视成功和影响的衡量标准。虽然与大型企业的研究合作富有成效,但促进企业创业的新努力正在改变机构如何看待学术创新与附属创业公司形成之间联系的好处。这种从创新到企业的关注可以帮助培养更广泛的捐赠者到投资者网络。虽然对医学物理学的未来方向有很多预测,但实际的发明和发现步骤来自于个别研究教师的创造力。所有通过 DIVERT 模型取得的成功都需要教师主导的倡议跨越从发明到转化的差距,同时在整个过程的各个步骤中得到机构领导层的支持。由于赠款的相对减少,机构通过捐赠或临床收入对教师的投资可能需要在未来几年增加。然而,放射学和放射肿瘤学都是高收入、转化型领域,通过相互受益的大型基础设施,有能力协同支持临床和研究运营。这些路线图原则可以为致力于学术领导的学术医学物理计划提供一条途径,以保持医学物理作为大学学术的活跃组成部分。