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一种在主动动态热成像(ADT)中产生高对比度静脉可视化的方法。

A method to produce high contrast vein visualization in active dynamic thermography (ADT).

机构信息

School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Ave, 639798, Singapore.

School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Ave, 639798, Singapore.

出版信息

Comput Biol Med. 2021 May;132:104309. doi: 10.1016/j.compbiomed.2021.104309. Epub 2021 Mar 6.

Abstract

In this study, a method that will aid in the visualization of vein topology on a target area on the body of a human subject is demonstrated. An external cooling means is configured to cool the left forearm of fourteen study participants, effecting an active thermal change or recovery in the target area upon removal of cooling. An infrared (IR) thermal camera was used to capture a series of transient thermal images. These images were then processed to extract Dynamic synthetic images (SI) throughout the active thermal change or recovery process. Dynamic SI was calculated using a quantitative parameter called tissue activity ratio (TAR), which is defined by the rate of rewarming to the rate of cooling at each pixel of interest. A fixed step size of rewarming temperature (0.5 °C) was used to progressively extract multiple synthetic images throughout the whole recovery process. Compared to a Static SI extraction method, where only a single SI results from the whole active dynamic thermography (ADT) sequence, this study demonstrates a live feed of high contrast vein visualizations by using the Dynamic SI method. Furthermore, the dependency of Dynamic SI contrast on the temperature of the external cooling stimulation was investigated. Three cooling stimulation temperatures (5 °C, 8 °C, and 11 °C) were tested, where no statistically significant difference in the resulting SI contrast was found. Lastly, a discussion is put forth on assisting venipuncture or cannulation-based clinical applications, through the incorporation of the proposed method with a projection system.

摘要

本研究展示了一种可在人体目标区域的静脉拓扑结构可视化的方法。外部冷却装置被配置为冷却十四名研究参与者的左前臂,在移除冷却时在目标区域引起主动热变化或恢复。一台红外(IR)热像仪被用于捕获一系列瞬态热图像。然后对这些图像进行处理,以在主动热变化或恢复过程中提取动态合成图像(SI)。使用称为组织活动比(TAR)的定量参数来计算动态 SI,该参数由每个感兴趣像素的复温率与冷却率定义。使用固定的复温温度步长(0.5°C)来逐步提取整个恢复过程中的多个合成图像。与仅从整个主动动态热成像(ADT)序列中获得单个 SI 的静态 SI 提取方法相比,本研究通过使用动态 SI 方法展示了高对比度静脉可视化的实时反馈。此外,还研究了动态 SI 对比度对外部冷却刺激温度的依赖性。测试了三种冷却刺激温度(5°C、8°C 和 11°C),结果发现 SI 对比度没有统计学上的显著差异。最后,通过将提出的方法与投影系统相结合,讨论了如何在静脉穿刺或插管等临床应用中提供辅助。

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