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Older Familial Hypercholesterolemia Patients with COVID-19.

作者信息

Vuorio Alpo, Kovanen Petri T, Strandberg Timo E

机构信息

Mehiläinen, Airport Health Center, Vantaa, Finland,

Department of Forensic Medicine, University of Helsinki, Helsinki, Finland,

出版信息

Gerontology. 2021;67(5):608-610. doi: 10.1159/000514447. Epub 2021 Mar 18.

DOI:10.1159/000514447
PMID:33735871
Abstract
摘要

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Older Familial Hypercholesterolemia Patients with COVID-19.老年家族性高胆固醇血症合并新型冠状病毒肺炎患者
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2
May statins and PCSK9 inhibitors be protective from COVID-19 in familial hypercholesterolemia subjects?他汀类药物和前蛋白转化酶枯草溶菌素9（PCSK9）抑制剂对家族性高胆固醇血症患者是否具有预防新型冠状病毒肺炎（COVID-19）的作用？
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Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors. A new drug class for the treatment of hypercholesterolemia.前蛋白转化酶枯草溶菌素/kexin 9型（PCSK9）抑制剂。一种用于治疗高胆固醇血症的新型药物类别。
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Apolipoprotein(a) phenotype determines the correlations of lipoprotein(a) and proprotein convertase subtilisin/kexin type 9 levels in patients with potential familial hypercholesterolemia.载脂蛋白(a)表型决定了潜在家族性高胆固醇血症患者脂蛋白(a)和前蛋白转化酶枯草溶菌素/克那霉 9 水平的相关性。
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How many familial hypercholesterolemia patients are eligible for PCSK9 inhibition?有多少家族性高胆固醇血症患者符合使用前蛋白转化酶枯草溶菌素9（PCSK9）抑制剂的条件？
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引用本文的文献

1
Familial Hypercholesterolemia Patients with COVID-19-Effective Cholesterol-Lowering Therapy is Urgent both during and after Infection.家族性高胆固醇血症合并新型冠状病毒肺炎患者——感染期间及感染后均急需有效的降胆固醇治疗
Rev Cardiovasc Med. 2022 Dec 19;23(12):410. doi: 10.31083/j.rcm2312410. eCollection 2022 Dec.
2
Patients with familial hypercholesterolemia and COVID-19: Efficient and ongoing cholesterol lowering is paramount for the prevention of acute myocardial infarction.家族性高胆固醇血症合并新冠病毒病患者：持续有效地降低胆固醇对于预防急性心肌梗死至关重要。
Am J Prev Cardiol. 2021 Sep;7:100224. doi: 10.1016/j.ajpc.2021.100224. Epub 2021 Jul 20.
3
Comment on: "Prior Treatment with Statins is Associated with Improved Outcomes of Patients with COVID-19: Data from the SEMI-COVID-19 Registry".
Drugs. 2021 Jun;81(9):1125-1127. doi: 10.1007/s40265-021-01537-7. Epub 2021 May 28.
4
Editorial: Genetics of Familial Hypercholesterolemia: New Insight.社论：家族性高胆固醇血症的遗传学：新见解
Front Genet. 2021 May 6;12:669373. doi: 10.3389/fgene.2021.669373. eCollection 2021.