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通过以患者为中心的护理解决口服免疫疗法中的实际挑战。

Practical challenges in oral immunotherapy resolved through patient-centered care.

作者信息

Graham François, Mack Douglas P, Bégin Philippe

机构信息

Allergy and Immunology, Centre Hospitalier de L'Université de Montréal, Hôpital Notre-Dame, Montreal, QC, Canada.

Allergy and Immunology, Centre Hospitalier Universitaire Sainte-Justine, 3175 Chemin de la Cote Sainte-Catherine, Montréal, QC, H3T1C5, Canada.

出版信息

Allergy Asthma Clin Immunol. 2021 Mar 18;17(1):31. doi: 10.1186/s13223-021-00533-6.

Abstract

Oral immunotherapy (OIT) is now widely recognized as a valid option for the management of IgE-mediated food allergies. However, in real-life practice, OIT can lead to a variety of unique situations where the best course of action is undetermined. In patient-centered care, individual patient preferences, needs and values, should guide all clinical decisions. This can be achieved by using shared-decision making and treatment customization to navigate areas of uncertainty in a way that is responsive to patient's needs and preferences. However, in the context of OIT, lack of awareness of potential protocol adaptability or alternatives can become a barrier to treatment personalization. The purpose of this article is to review the theoretical bases of patient-centered care and shared decision-making and their practical implication for the patient-centered delivery of OIT. Clinical cases highlighting common challenges in real-life OIT practice are presented along with a discussion of potential personalized management options to be considered. While the practice of OIT is bound to evolve as additional scientific and experiential knowledge is gained, it should always remain rooted in the general principles of patient-centered care.

摘要

口服免疫疗法(OIT)如今已被广泛认可为治疗IgE介导的食物过敏的一种有效选择。然而,在实际临床实践中,OIT可能会导致出现各种最佳行动方案尚未确定的独特情况。在以患者为中心的医疗中,患者的个人偏好、需求和价值观应指导所有临床决策。这可以通过采用共同决策和治疗定制来实现,以便以响应患者需求和偏好的方式应对不确定性领域。然而,在OIT的背景下,对潜在方案适应性或替代方案缺乏认识可能会成为治疗个性化的障碍。本文旨在回顾以患者为中心的医疗和共同决策的理论基础及其对以患者为中心的OIT实施的实际意义。文中呈现了突出实际OIT临床实践中常见挑战的临床案例,并讨论了可供考虑的潜在个性化管理方案。虽然随着获得更多的科学和实践知识,OIT的实践必然会不断发展,但它应始终扎根于以患者为中心的医疗的一般原则。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b20/7977307/c2cb262ea9ed/13223_2021_533_Fig1_HTML.jpg

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