Burke J J, Fischer P M
Department of Family Medicine, Medical College of Georgia, Augusta 30912.
JAMA. 1988 Jun 17;259(23):3444-8.
The office laboratory has the potential to be an ideal setting for cholesterol testing if accurate test results are achieved. This study describes the performance of three office chemistry analyzers (Abbott Vision, Boehringer-Mannheim Reflotron, and Kodak Ektachem DT60 Analyzer) in the measurement of cholesterol. The accuracy of these instruments was assessed by testing aliquots of 84 plasma specimens and comparing these results with values obtained in one of the National Heart, Lung, and Blood Institute's Lipid Research Clinic laboratories. To evaluate instrument precision, results from each of the three instruments were compared with the cholesterol standards recently released by the College of American Pathologists. When operated according to the manufacturers' recommended procedures, each of the three instruments demonstrated analytic capabilities that met the current accuracy and precision goals established by the National Cholesterol Education Program. Analytic issues that are pertinent to the clinician's role as both the office laboratory director and the test interpreter are reviewed.
如果能获得准确的检测结果，门诊实验室有潜力成为进行胆固醇检测的理想场所。本研究描述了三种门诊化学分析仪（雅培Vision、勃林格殷格翰Reflotron和柯达Ektachem DT60分析仪）在胆固醇测量中的性能表现。通过检测84份血浆标本的等分试样，并将这些结果与在美国国立心肺血液研究所脂质研究诊所之一所获得的值进行比较，评估了这些仪器的准确性。为评估仪器的精密度，将三种仪器各自的结果与美国病理学家学会最近发布的胆固醇标准进行了比较。当按照制造商推荐的程序操作时，这三种仪器均展示出了符合国家胆固醇教育计划所确立的当前准确性和精密度目标的分析能力。本文还对与临床医生作为门诊实验室主任和检测结果解读者这两个角色相关的分析问题进行了综述。
