Department of Nursing, Shengjing Hospital of China Medical University, Shenyang, 110004, Liaoning Province, People's Republic of China.
Sci Rep. 2021 Mar 18;11(1):6371. doi: 10.1038/s41598-021-85794-2.
We determined if the increasing trend in hypertension can be partly attributed to increasing prevalence of overweight/obesity in China over the past two decades. Data were collected from 1991 to 2011 and the population attributable risk (PAR), which is used to estimate the intervention effect on hypertension if overweight/obese, were eliminated. Linear regression was used to evaluate the secular trends. The age-standardized prevalence of overweight and obesity increased by 26.32% with an overall slope of 1.27% (95% CI: 1.12-1.43%) per year. Hypertension also increased by 12.37% with an overall slope of 0.65% (95% CI: 0.51-0.79%) per year. The adjusted ORs of overweight/obesity for hypertension across the survey years remained unchanged; however, the trend in PAR increased steadily from 27.1 to 44.6% with an overall slope of 0.81% (95% CI: 0.34-1.28%) per year (P = 0.006). There was no significant gender difference in the slopes of increasing PAR, as measured by regression coefficients (β = 0.95% vs. β = 0.63% per year, P = 0.36). Over the past two decades, the increase in the prevalence of hypertension in China was partly attributed to the overweight/obesity epidemic, which highlights the importance of controlling weight and further reducing the burden of hypertension.
我们旨在探讨过去二十年来中国超重/肥胖流行率的上升是否可以部分归因于高血压发病率的上升。本研究的数据收集于 1991 年至 2011 年,通过消除人群归因风险(PAR)来评估超重/肥胖对高血压的干预效果。采用线性回归评估其时间趋势。结果显示,超重和肥胖的年龄标准化患病率增加了 26.32%,总体斜率为每年 1.27%(95%可信区间:1.12-1.43%)。同期高血压的患病率也增加了 12.37%,总体斜率为每年 0.65%(95%可信区间:0.51-0.79%)。调整后的超重/肥胖与高血压的比值(OR)在整个研究期间保持不变;然而,PAR 的趋势却稳步上升,从 27.1%增加到 44.6%,每年增加 0.81%(95%可信区间:0.34-1.28%)(P = 0.006)。PAR 斜率的增加在性别之间没有显著差异,用回归系数表示(β = 0.95% vs. β = 0.63%/年,P = 0.36)。过去二十年来,中国高血压患病率的上升部分归因于超重/肥胖流行,这凸显了控制体重和进一步降低高血压负担的重要性。
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