Department of Marine Chemistry, Khorramshahr University of Marine Science and Technology, P.O. Box 669, Khorramshahr, Iran.
Department of Chemistry, Payame Noor University, P.O. Box 19395-3697, Tehran, Iran.
Sci Rep. 2021 Mar 18;11(1):6296. doi: 10.1038/s41598-021-85832-z.
This research presents a novel biological route for the biosynthesis of nickel oxide nanoparticles (NiO NPs) using marine macroalgae extract as a reducing and coating agent under optimized synthesis conditions. XRD and TEM analyses revealed that phytosynthesized NiO NPs are crystalline in nature with a spherical shape having a mean particle size of 32.64 nm. TGA results indicated the presence of marine-derived organic constituents on the surface of NiO NPs. It is found that biogenic NiO NPs with BET surface area of 45.59 mg is a highly efficient catalyst for benign one-pot preparation of pyridopyrimidine derivatives using aqueous reaction conditions. This environmentally friendly procedure takes considerable advantages of shorter reaction times, excellent product yields (up to 96%), magnetically viable nanocatalyst (7 runs), low catalyst loadings, and free toxic chemical reagents.
本研究提出了一种新颖的生物合成路线，使用海洋大型藻类提取物作为还原剂和包覆剂，在优化的合成条件下合成氧化镍纳米粒子（NiO NPs）。XRD 和 TEM 分析表明，所合成的 NiO NPs 为结晶性，具有球形形貌，平均粒径为 32.64nm。TGA 结果表明，NiO NPs 表面存在海洋衍生的有机成分。研究发现，生物合成的 NiO NPs 具有 BET 比表面积 45.59mg，是一种高效的催化剂，可在水相反应条件下温和地一锅法制备吡啶并嘧啶衍生物。该绿色环保方法具有反应时间短、产率高（高达 96%）、可回收利用的磁性纳米催化剂（7 次循环）、低催化剂用量和无毒性化学试剂等优点。
