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贫血预示着乙肝相关性失代偿期肝硬化患者的不良预后。

Anemia Predicts Poor Outcomes in Patients with HBV-Related Decompensated Cirrhosis.

作者信息

Cai Ming, Yang Na, Lin Sha, Ye Bo, Chen Hui, Mao Wei-Lin

出版信息

Clin Lab. 2021 Mar 1;67(3). doi: 10.7754/Clin.Lab.2020.200701.

Abstract

BACKGROUND

Anemia is common in patients with severe chronic liver disease, but its role in HBV-related decompensated cirrhosis (DeCi) is still unclear. We therefore aimed to assess the impact of anemia on prognosis in HBV-DeCi patients.

METHODS

One hundred thirty-three patients diagnosed with HBV-DeCi were retrospectively collected.

RESULTS

A total of 113 (85.0%) patients suffered from anemia in our cohort. The low hemoglobin (Hb) level group exhibited a significantly increased 28-day mortality rate compared with the high Hb group. Hb level was a predictor of 28-day mortality in HBV-DeCi patients.

CONCLUSIONS

Reduced Hb levels were associated with unfavorable prognosis in HBV-DeCi patients, and more attention should be paid to anemia in routine clinical assessments of liver cirrhosis.

摘要

背景

贫血在严重慢性肝病患者中很常见,但其在乙型肝炎病毒(HBV)相关失代偿期肝硬化(DeCi)中的作用仍不清楚。因此,我们旨在评估贫血对HBV-DeCi患者预后的影响。

方法

回顾性收集133例诊断为HBV-DeCi的患者。

结果

在我们的队列中,共有113例(85.0%)患者患有贫血。与高血红蛋白(Hb)组相比,低Hb水平组的28天死亡率显著增加。Hb水平是HBV-DeCi患者28天死亡率的预测指标。

结论

Hb水平降低与HBV-DeCi患者的不良预后相关,在肝硬化的常规临床评估中应更加关注贫血。

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