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贫血预示着乙肝相关性失代偿期肝硬化患者的不良预后。

Anemia Predicts Poor Outcomes in Patients with HBV-Related Decompensated Cirrhosis.

作者信息

Cai Ming, Yang Na, Lin Sha, Ye Bo, Chen Hui, Mao Wei-Lin

出版信息

Clin Lab. 2021 Mar 1;67(3). doi: 10.7754/Clin.Lab.2020.200701.

DOI:10.7754/Clin.Lab.2020.200701
PMID:33739043
Abstract

BACKGROUND

Anemia is common in patients with severe chronic liver disease, but its role in HBV-related decompensated cirrhosis (DeCi) is still unclear. We therefore aimed to assess the impact of anemia on prognosis in HBV-DeCi patients.

METHODS

One hundred thirty-three patients diagnosed with HBV-DeCi were retrospectively collected.

RESULTS

A total of 113 (85.0%) patients suffered from anemia in our cohort. The low hemoglobin (Hb) level group exhibited a significantly increased 28-day mortality rate compared with the high Hb group. Hb level was a predictor of 28-day mortality in HBV-DeCi patients.

CONCLUSIONS

Reduced Hb levels were associated with unfavorable prognosis in HBV-DeCi patients, and more attention should be paid to anemia in routine clinical assessments of liver cirrhosis.

摘要

背景

贫血在严重慢性肝病患者中很常见,但其在乙型肝炎病毒(HBV)相关失代偿期肝硬化(DeCi)中的作用仍不清楚。因此,我们旨在评估贫血对HBV-DeCi患者预后的影响。

方法

回顾性收集133例诊断为HBV-DeCi的患者。

结果

在我们的队列中,共有113例(85.0%)患者患有贫血。与高血红蛋白(Hb)组相比,低Hb水平组的28天死亡率显著增加。Hb水平是HBV-DeCi患者28天死亡率的预测指标。

结论

Hb水平降低与HBV-DeCi患者的不良预后相关,在肝硬化的常规临床评估中应更加关注贫血。

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引用本文的文献

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Elevated neutrophil-to-hemoglobin ratio as an indicator of poor survival in hepatitis B virus-related decompensated cirrhosis.中性粒细胞与血红蛋白比值升高作为乙型肝炎病毒相关失代偿期肝硬化患者生存不良的指标
Biomark Med. 2024;18(9):477-483. doi: 10.1080/17520363.2024.2352420. Epub 2024 Jun 17.
2
Low Hemoglobin-to-Red Cell Distribution Width Ratio Is Associated with Mortality in Patients with HBV-Related Decompensated Cirrhosis.低血红蛋白与红细胞分布宽度比值与 HBV 相关失代偿性肝硬化患者的死亡率相关。
Biomed Res Int. 2022 Feb 14;2022:5754790. doi: 10.1155/2022/5754790. eCollection 2022.