Zhang Tan, Mao WeiLin
Department of Clinical Laboratory, Shengzhou People's Hospital, Shengzhou Branch of the First Affiliated Hospital of Zhejiang University, Shengzhou, 312400, China.
Department of Clinical Laboratory, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310003, China.
Biomark Med. 2024;18(9):477-483. doi: 10.1080/17520363.2024.2352420. Epub 2024 Jun 17.
Our goal was to explore the prognostic value of the neutrophil-to-hemoglobin ratio (NHR) in HBV-related decompensated cirrhosis (HBV-DC) patients. 172 HBV-DC patients were enrolled. Multivariate analyses were used to identify risk factors influencing 30-day mortality. The 30-day mortality was 12.8% (22/172). nonsurvivors exhibited a higher NHR than survivors. On multivariate analysis, NHR and model for end-stage liver disease (MELD) score were the only independent predictors of mortality. Notably, the predictive capabilities of NHR were found to be comparable to those of the MELD score. High NHR was associated with poor prognosis in HBV-DC patients, and NHR can serve as an effective and readily available indicator for the prediction of mortality in these patients.
我们的目标是探讨中性粒细胞与血红蛋白比值（NHR）在乙型肝炎病毒相关失代偿期肝硬化（HBV-DC）患者中的预后价值。纳入了172例HBV-DC患者。采用多因素分析来确定影响30天死亡率的危险因素。30天死亡率为12.8%（22/172）。非幸存者的NHR高于幸存者。多因素分析显示，NHR和终末期肝病模型（MELD）评分是死亡率的唯一独立预测因素。值得注意的是，发现NHR的预测能力与MELD评分相当。高NHR与HBV-DC患者的不良预后相关，NHR可作为预测这些患者死亡率的有效且易于获得的指标。
