以非快速眼动睡眠为主的可逆性矛盾呼吸努力表明多系统萎缩中膈肌运动失调。
Non-REM sleep-predominant reversible paradoxical breathing effort indicates dysregulation of diaphragm movements in multiple system atrophy.
作者信息
Ha Jongmok, Park Jaehong, Youn Jinyoung, Cho Jin Whan, Joo Eun Yeon
机构信息
Department of Neurology, Neuroscience Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
出版信息
J Clin Sleep Med. 2021 Jul 1;17(7):1499-1502. doi: 10.5664/jcsm.9256.
STUDY OBJECTIVES
In multiple system atrophy, sleep-disordered breathing has a broad spectrum of phenotypes, among them inspiratory stridor and obstructive sleep apnea being most frequent.
METHODS
We present a case of a 59-year-old woman with cerebellar-type multiple system atrophy, who showed transient paradoxical breathing effort during non-rapid eye movement sleep on diagnostic polysomnography. Because this thoraco-abdominal paradox was atypical for and did not coincide with upper airway obstruction, it most likely indicated central dysregulation of the diaphragm.
RESULTS
Continuous positive airway pressure therapy with low pressure (5 cm H₂O) was sufficient to completely resolve this type of respiratory dysregulation.
CONCLUSIONS
This case extends the clinical spectrum of sleep-disordered breathing in multiple system atrophy.
研究目的
在多系统萎缩中，睡眠呼吸障碍具有广泛的表型，其中吸气性喘鸣和阻塞性睡眠呼吸暂停最为常见。
方法
我们报告一例59岁小脑型多系统萎缩女性患者，其在诊断性多导睡眠图检查的非快速眼动睡眠期间出现短暂的矛盾呼吸努力。由于这种胸腹矛盾呼吸对于上气道阻塞而言不典型且与之不符，因此很可能提示膈肌的中枢调节异常。
结果
低压（5 cm H₂O）持续气道正压通气治疗足以完全解决这类呼吸调节异常。
结论
该病例扩展了多系统萎缩中睡眠呼吸障碍的临床谱。
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