School of Kinesiology and Health Sciences, York University, Toronto, Ontario, Canada.
Division of Sports Medicine, Graduate School of Physical Education, Kyung Hee University, Yongin, Republic of Korea.
Child Obes. 2021 Jun;17(4):249-256. doi: 10.1089/chi.2020.0280. Epub 2021 Mar 18.
We examined the effects of exercise training on resting metabolic rate (RMR), and whether changes in body composition are associated with changes in RMR in adolescents with overweight and obesity. One hundred forty adolescents (12-18 years, BMI ≥85th percentile) participated in randomized exercise trials (3-6 months) at UPMC Children's Hospital of Pittsburgh (18 control, 51 aerobic, 50 resistance, and 21 combined aerobic and resistance exercise). All participants had RMR assessments by indirect calorimetry after a 10-12 hour overnight fast, and body composition by magnetic resonance imaging and dual-energy X-ray absorptiometry. There were no significant changes in RMR (kcal/day) between exercise groups vs. controls ( > 0.05). All exercise groups decreased visceral fat (-0.2 ± 0.02 kg; < 0.05) compared to control. Increases in fat-free mass (FFM) were only seen in the combined group (2.3 ± 0.4 kg; < 0.05), whereas increases in skeletal muscle mass were observed in both resistance (1.2 ± 0.2 kg; < 0.05) and combined (1.5 ± 0.3 kg; < 0.05) groups vs. control. Change in FFM, but not fat mass (FM), visceral fat, or skeletal muscle mass ( > 0.05), was a significant determinant of changes in RMR, independent of exercise modality ( = 0.04). Although exercise modality was not associated with changes in RMR, change in FFM, but not skeletal muscle or FM, was a significant correlate of changes in RMR in adolescents with overweight and obesity. Clinicaltrials.gov registration numbers: NCT00739180, NCT01323088, NCT01938950.
我们研究了运动训练对静息代谢率（RMR）的影响，以及超重和肥胖青少年的身体成分变化是否与 RMR 的变化相关。140 名青少年（12-18 岁，BMI≥第 85 百分位）参加了匹兹堡大学医学中心儿童医院（18 名对照组、51 名有氧运动组、50 名抗阻运动组和 21 名有氧与抗阻联合运动组）的随机运动试验（3-6 个月）。所有参与者在禁食 10-12 小时后通过间接测热法进行 RMR 评估，并通过磁共振成像和双能 X 射线吸收法进行身体成分评估。与对照组相比，运动组的 RMR（千卡/天）没有显著变化（>0.05）。与对照组相比，所有运动组的内脏脂肪（-0.2±0.02kg；<0.05）均减少。仅在联合组中观察到去脂体重（FFM）增加（2.3±0.4kg；<0.05），而在抗阻组（1.2±0.2kg；<0.05）和联合组（1.5±0.3kg；<0.05）中均观察到骨骼肌质量增加。FFM 的变化，而不是脂肪质量（FM）、内脏脂肪或骨骼肌质量（>0.05），是 RMR 变化的一个重要决定因素，与运动方式无关（=0.04）。尽管运动方式与 RMR 的变化无关，但 FFM 的变化，而不是骨骼肌或 FM 的变化，与超重和肥胖青少年 RMR 的变化有显著相关性。Clinicaltrials.gov 注册号：NCT00739180、NCT01323088、NCT01938950。
