Exerc Sport Sci Rev. 2021 Apr 1;49(2):115-125. doi: 10.1249/JES.0000000000000242.
One of the best strategies for healthy brain aging is regular aerobic exercise. Commonly studied "anti-aging" compounds may mimic some effects of exercise on the brain, but novel approaches that target energy-sensing pathways similar to exercise probably will be more effective in this context. We review evidence in support of this hypothesis by focusing on biological hallmarks of brain aging.
保持大脑健康的最佳策略之一是定期进行有氧运动。通常研究的“抗衰老”化合物可能模拟运动对大脑的某些影响,但针对类似于运动的能量感应途径的新方法在这种情况下可能更有效。我们通过关注大脑老化的生物学特征来回顾支持这一假设的证据。