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健康大脑衰老的新策略。

Novel Strategies for Healthy Brain Aging.

出版信息

Exerc Sport Sci Rev. 2021 Apr 1;49(2):115-125. doi: 10.1249/JES.0000000000000242.

DOI:10.1249/JES.0000000000000242
PMID:33739944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7967995/
Abstract

One of the best strategies for healthy brain aging is regular aerobic exercise. Commonly studied "anti-aging" compounds may mimic some effects of exercise on the brain, but novel approaches that target energy-sensing pathways similar to exercise probably will be more effective in this context. We review evidence in support of this hypothesis by focusing on biological hallmarks of brain aging.

摘要

保持大脑健康的最佳策略之一是定期进行有氧运动。通常研究的“抗衰老”化合物可能模拟运动对大脑的某些影响，但针对类似于运动的能量感应途径的新方法在这种情况下可能更有效。我们通过关注大脑老化的生物学特征来回顾支持这一假设的证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0680/7967995/420e14f0f6e2/nihms-1656166-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0680/7967995/ef7908367d73/nihms-1656166-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0680/7967995/e928945155a5/nihms-1656166-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0680/7967995/cfc7d64a426b/nihms-1656166-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0680/7967995/420e14f0f6e2/nihms-1656166-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0680/7967995/ef7908367d73/nihms-1656166-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0680/7967995/e928945155a5/nihms-1656166-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0680/7967995/cfc7d64a426b/nihms-1656166-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0680/7967995/420e14f0f6e2/nihms-1656166-f0004.jpg

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本文引用的文献

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Acute increases in brain-derived neurotrophic factor following high or moderate-intensity exercise is accompanied with better cognition performance in obese adults.肥胖成年人在进行高强度或中等强度运动后，大脑源性神经营养因子会急性增加，伴随而来的是更好的认知表现。
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