Kumagai Hiroshi, Myoenzono Kanae, Yoshikawa Toru, Tsujimoto Takehiko, Shimomura Kosei, Maeda Seiji
Division of Sports Medicine, Faculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan.
Graduate School of Health and Sports Science, Juntendo University, Chiba, Japan.
Aging Male. 2020 Dec;23(5):1194-1201. doi: 10.1080/13685538.2020.1724940. Epub 2020 Feb 12.
The leading cause of aging-induced male-specific disorders such as physical, mental and/or sexual symptoms is testosterone deficiency. Although aerobic exercise is suggested to improves circulating testosterone levels, physical fitness, depressive symptoms, and sexual function, the effect of regular aerobic exercise on aging-induced disorders has not yet been clarified. Here we performed cross-sectional and interventional studies to identify the effect of aerobic exercise on aging-induced disorders assessed by the Aging Males' Symptoms questionnaire (AMS). In study 1, the relationship between aerobic exercise capacity (i.e. peak oxygen consumption) and AMS scores were cross-sectionally examined in 169 adult men. In study 2, the effect of a 12-week regular aerobic exercise on AMS scores was longitudinally investigated in 18 adult men. In study 1, the AMS-total, AMS-somatic, AMS-psychological, and AMS-sexual scores were significantly correlated to aerobic exercise capacity even after considering age and testosterone levels. In study 2, 12-week aerobic exercise training significantly improved AMS-sexual and tended to improve AMS-total scores. Additionally, an increase in vigorous physical activity was correlated to improve in the AMS-sexual score. These results suggest that regular aerobic exercise is an effective strategy to improve aging-induced disorders in men.
衰老引发的男性特有疾病，如身体、心理和/或性功能症状，其主要原因是睾酮缺乏。尽管有建议称有氧运动可提高循环睾酮水平、增强身体素质、改善抑郁症状和性功能，但规律有氧运动对衰老引发疾病的影响尚未明确。在此，我们进行了横断面研究和干预性研究，以确定有氧运动对通过男性衰老症状问卷（AMS）评估的衰老引发疾病的影响。在研究1中，对169名成年男性进行横断面检查，分析有氧运动能力（即最大摄氧量）与AMS评分之间的关系。在研究2中，对18名成年男性进行纵向研究，探讨为期12周的规律有氧运动对AMS评分的影响。在研究1中，即使考虑年龄和睾酮水平，AMS总分、AMS躯体症状评分、AMS心理症状评分和AMS性功能评分仍与有氧运动能力显著相关。在研究2中，为期12周的有氧运动训练显著改善了AMS性功能评分，并使AMS总分有改善趋势。此外，剧烈身体活动的增加与AMS性功能评分的改善相关。这些结果表明，规律有氧运动是改善男性衰老引发疾病的有效策略。
