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功能梯度材料对骨整合股骨假体周围骨重建的影响。

The effect of functionally graded materials on bone remodeling around osseointegrated trans-femoral prostheses.

机构信息

Department of Mechanical Engineering, Hakim Sabzevari University, Sabzevar, Iran.

Department of Mechanical Engineering, Hakim Sabzevari University, Sabzevar, Iran.

出版信息

J Mech Behav Biomed Mater. 2021 Jun;118:104426. doi: 10.1016/j.jmbbm.2021.104426. Epub 2021 Mar 13.

DOI:10.1016/j.jmbbm.2021.104426
PMID:33740685
Abstract

Osseointegrated trans-femoral fixations have been used as alternatives for conventional sockets in recent years. Despite numerous advantages, the dissimilarity of the mechanical properties between bone and implant has led to issues in periprosthetic bone adaptation. This study aims to address these issues by proposing fixations made of functionally graded materials (FGMs). The computational study of bone remodeling was performed by linking a bone remodeling algorithm to the finite element analysis. The 3D model of the femur was created by computerized tomography (CT) scan images, and a Titanium fixture, along with nine Titanium/Hydroxyapatite FGM fixtures, were modeled. The analyses revealed evident advantages for the FGM fixtures over the conventionally used Titanium fixtures. Furthermore, it was shown that the gradation direction considerably affects the bone adaptation procedure. The results showed that using a radial FGM with low-stiffness material in the outer layer and less metal composition significantly improves the bone remodeling behavior.

摘要

近年来,骨整合式经股骨固定已被用作传统插座的替代品。尽管具有许多优点,但骨骼和植入物之间机械性能的不相似性导致了假体周围骨骼适应性的问题。本研究旨在通过提出由功能梯度材料(FGM)制成的固定装置来解决这些问题。通过将骨重塑算法与有限元分析联系起来,进行骨重塑的计算研究。股骨的 3D 模型是通过计算机断层扫描(CT)扫描图像创建的,并且模拟了钛固定器以及九个钛/羟基磷灰石 FGM 固定器。分析表明,FGM 固定器明显优于传统使用的钛固定器。此外,还表明渐变方向会极大地影响骨骼适应过程。结果表明,在外层使用具有低刚度材料的径向 FGM 并减少金属成分可以显著改善骨重塑行为。

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