Research Department of Primary Care and Population Health, University College London, London, UK
Research Department of Primary Care and Population Health, University College London, London, UK.
BMJ Open Diabetes Res Care. 2021 Mar;9(1). doi: 10.1136/bmjdrc-2020-001989.
To describe recent trends in the incidence of clinically diagnosed type 2 diabetes and pre-diabetes in people seen in UK general practice.
A retrospective cohort study using IQVIA Medical Research Data looking at people newly diagnosed with type 2 diabetes and pre-diabetes through primary care registers in the UK between 1 January 2009 and 31 December 2018.
A cohort of 426 717 people were clinically diagnosed with type 2 diabetes and 418 656 people met the criteria for a diagnosis of pre-diabetes in that time period. The incidence of clinically diagnosed type 2 diabetes per 1000 person years at risk (PYAR) in men decreased from a peak of 5.06 per 1000 PYAR (95% CI 4.97 to 5.15) in 2013 to 3.56 per 1000 PYAR (95% CI 3.46 to 3.66) by 2018. For women, the incidence of clinically diagnosed type 2 diabetes per 1000 PYAR decreased from 4.45 (95% CI 4.37 to 4.54) in 2013 to 2.85 (2.76 to 2.93) in 2018. The incidence rate of pre-diabetes tripled by the end of the same study period in men and women.
Between 2009 and 2018, the incidence rate of new clinical diagnoses of type 2 diabetes recorded in a UK primary care database decreased by a third from its peak in 2013-2014, while the incidence of pre-diabetes has tripled. The implications of this on timely treatment, complication rates and mortality need further longer term exploration.
描述英国普通诊所中临床诊断的 2 型糖尿病和糖尿病前期的发病率最近的趋势。
这是一项使用 IQVIA 医疗研究数据的回顾性队列研究，该研究观察了 2009 年 1 月 1 日至 2018 年 12 月 31 日期间通过英国初级保健登记处新诊断出 2 型糖尿病和糖尿病前期的人群。
在这段时间内，426717 人被临床诊断为 2 型糖尿病，418656 人符合糖尿病前期的诊断标准。男性每 1000 人风险年（PYAR）临床诊断的 2 型糖尿病发病率从 2013 年的峰值 5.06/1000 PYAR（95%CI 4.97 至 5.15）下降到 2018 年的 3.56/1000 PYAR（95%CI 3.46 至 3.66）。对于女性，每 1000 人风险年（PYAR）临床诊断的 2 型糖尿病发病率从 2013 年的 4.45（95%CI 4.37 至 4.54）下降到 2018 年的 2.85（2.76 至 2.93）。在同一研究期间结束时，男性和女性的糖尿病前期发病率增加了两倍。
在 2009 年至 2018 年期间，英国初级保健数据库中记录的新临床诊断 2 型糖尿病的发病率从 2013-2014 年的峰值下降了三分之一，而糖尿病前期的发病率增加了两倍。这对及时治疗、并发症发生率和死亡率的影响需要进一步的长期探索。
