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下颌骨青少年砂粒体样牙骨质骨化纤维瘤:诊断难题。

Juvenile Psammomatoid Cemeto-ossifying Fibroma of Mandible: a Diagnostic dilemma.

作者信息

Rao Santhosh, Singh Vandita, Hafeez A Abdul, Agarwal Subham S

机构信息

Dentistry-Oral & Maxillofacial Surgey, All India Institute of Medical Sciences-Raipur, Raipur, Tatibandh, India

Pathology and Laboratory Medicine, All India Institute of Medical Sciences-Raipur, Raipur, Chhattisgardh, India.

出版信息

BMJ Case Rep. 2021 Mar 19;14(3):e240952. doi: 10.1136/bcr-2020-240952.

Abstract

Psammomatoid Juvenile ossifying fibroma (PsJOF) is a rare benign fibro-osseous lesion characterised to grow to unusually large size very rapidly. Its usual presentation is in younger age group mostly children and predominately involving the Sino-Naso-Orbital region. Its aggressive nature gimmicks a malignant lesion but it is rather a benign lesion with a higher recurrence rate than the conventional ossifying fibroma but lacking metastatic potential. The high recurrence rate makes it essential that the lesion is not reconstructed immediately and thorough monitoring in the follow-up period. Lesion of such clinical importance needs to be diagnosed preoperatively to provide a better and radical surgical treatment option, but the variability in its presentation as seen in this case makes it even harder to diagnose. We aim to draw attention to the rare phenomena that PsJOF presents to help readers broaden their purview in diagnosis and thereby manage them accordingly.

摘要

砂粒样幼年骨化性纤维瘤(PsJOF)是一种罕见的良性纤维骨性病变,其特征是生长迅速且异常巨大。它通常发生在较年轻的年龄组,主要是儿童,且主要累及鼻窦-鼻-眶区域。其侵袭性特征易让人误以为是恶性病变,但它实际上是一种良性病变,复发率高于传统骨化性纤维瘤,但缺乏转移潜能。高复发率使得在随访期间不立即重建病变并进行彻底监测至关重要。具有如此临床重要性的病变需要在术前进行诊断,以提供更好的根治性手术治疗方案,但如本病例所见,其表现的变异性使得诊断更加困难。我们旨在引起对PsJOF所呈现的罕见现象的关注,以帮助读者拓宽诊断视野,从而相应地进行管理。

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本文引用的文献

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Ossifying fibroma: a clinicopathologic study of sixty-four cases.骨化性纤维瘤:64例临床病理研究
Oral Surg Oral Med Oral Pathol. 1985 Nov;60(5):505-11. doi: 10.1016/0030-4220(85)90239-7.

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