原发性和继发性早泄患者与健康对照者阴茎背神经躯体感觉诱发电位检测的差异研究。

A Study of Differences in Penile Dorsal Nerve Somatosensory Evoked Potential Testing Among Healthy Controls and Patients With Primary and Secondary Premature Ejaculation.

机构信息

The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.

Department of Urology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China; Andrology Laboratory on Integration of Chinese and Western Medicine, Zhejiang Provincial Key Laboratory of Traditional Chinese Medicine, Hangzhou, China.

出版信息

J Sex Med. 2021 Apr;18(4):732-736. doi: 10.1016/j.jsxm.2021.01.186. Epub 2021 Mar 18.

DOI:10.1016/j.jsxm.2021.01.186

PMID:33744179

Abstract

BACKGROUND

Penile dorsal nerve somatosensory evoked potential (DNSEP) is a scientific and objective technique that provides effective and objective data to establish the diagnosis of premature ejaculation (PE).

AIM

To explore differences in DNSEP between patients with primary premature ejaculation (PPE) and those with secondary premature ejaculation (SPE), in order to investigate the clinical value of DNSEP in the diagnosis of PE.

METHODS

The participants were divided into a PPE group (34 cases), an SPE group (25 cases) and a healthy control group (18 cases). All participants underwent DNSEP testing, and the latencies and amplitudes of DNSEP were recorded.

OUTCOMES

Differences in the latencies and amplitudes of DNSEP were compared among the PPE, SPE, and healthy control groups.

RESULTS

The latencies of DNSEP in the PPE and SPE groups were shorter than those in the healthy control group, and these differences were statistically significant (P < 0.01). However, there was no statistically significant difference between the PPE and SPE groups (P > 0.05). The amplitudes of DNSEP in the PPE group were significantly higher than those in the healthy control group (P < 0.01). However, the amplitudes of DNSEP in the SPE group were significantly lower than those in the healthy control group (P < 0.05).

CLINICAL IMPLICATIONS

PPE and SPE can be differentiated based on differences in the amplitudes of DNSEP, providing an objective basis for treatments and follow-up examinations.

STRENGTHS AND LIMITATIONS

We evaluated differences in the amplitudes of DNSEP between PPE and SPE patients, which were rare in the published literature. However, specific causes of these differences are still unclear. SEP only reflects afferent pathways in the ejaculatory reflex arc, and role of the brain as a higher center should not be ignored.

CONCLUSION

Both PPE and SPE patients are characterized by an increased excitability of the penile sensory nerves. Sun Z, Liao Z, Zheng Q, et al. A Study of Differences in Penile Dorsal Nerve Somatosensory Evoked Potential Testing Among Healthy Controls and Patients With Primary and Secondary Premature Ejaculation. J Sex Med Rev 2021;18:732-736.

摘要

背景

阴茎背神经体感诱发电位（DNSEP）是一种科学客观的技术，可提供有效的客观数据，从而建立早泄（PE）的诊断。

目的

探讨原发性早泄（PPE）和继发性早泄（SPE）患者之间的 DNSEP 差异，以探讨 DNSEP 在 PE 诊断中的临床价值。

方法

将参与者分为 PPE 组（34 例）、SPE 组（25 例）和健康对照组（18 例）。所有参与者均接受 DNSEP 测试，并记录 DNSEP 的潜伏期和振幅。

结果

比较 PPE、SPE 和健康对照组之间 DNSEP 的潜伏期和振幅差异。

结果

PPE 和 SPE 组的 DNSEP 潜伏期短于健康对照组，差异有统计学意义（P < 0.01）。然而，PPE 和 SPE 组之间没有统计学差异（P > 0.05）。PPE 组的 DNSEP 振幅明显高于健康对照组（P < 0.01）。然而，SPE 组的 DNSEP 振幅明显低于健康对照组（P < 0.05）。