School of Chemical Engineering and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, 710049, China.
School of Chemical Engineering and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, 710049, China.
Biosens Bioelectron. 2021 Jun 1;181:113164. doi: 10.1016/j.bios.2021.113164. Epub 2021 Mar 13.
The ingenious design and synthesis of novel macrocycles bring out renewed vigor of supramolecular chemistry in the past decade. As an intriguing class of macrocycles, pillararene and pillararene-based functional materials that are constructed through the noncovalent bond self-assembly approach have been undergoing a rapid growth, benefiting from their unique structures and physiochemical properties. This review elaborates recent significant advances of electrochemical studies based on pillararene systems. Fundamental electrochemical behavior of pillar[n]arene[m]quinone and pillararene-based self-assemblies as well as their applications in electrochemical biosensors are highlighted. In addition, the advantages and functions of pillararene self-assembly systems resulted from the unique molecular architectures are analyzed. Finally, current challenges and future development tendency in this burgeoning field are discussed from the viewpoint of both fundamental research and applications. Overall, this review not only manifests the main development vein of pillararene-based electrochemical systems, but also conquers a solid foundation for their further bioelectrochemical applications.
在过去的十年中，新颖大环的巧妙设计和合成给超分子化学带来了新的活力。作为一类有趣的大环，通过非共价键自组装方法构建的杯芳烃和杯芳烃基功能材料由于其独特的结构和物理化学性质而迅速发展。本文综述了基于杯芳烃体系的电化学研究的最新重要进展。重点介绍了杯[n]芳烃[ m]醌和杯芳烃基自组装作为电化学生物传感器的基本电化学行为及其应用。此外，还分析了杯芳烃自组装体系由于独特的分子结构而产生的优势和功能。最后，从基础研究和应用两个方面讨论了这个新兴领域目前的挑战和未来的发展趋势。总的来说，本综述不仅体现了基于杯芳烃的电化学体系的主要发展脉络，而且为其进一步的生物电化学应用奠定了坚实的基础。
