Li Xing, Ao Mingyue, Zhang Chunling, Fan Shunming, Chen Zhimin, Yu Lingying
College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 6111137, China.
Evid Based Complement Alternat Med. 2021 Mar 2;2021:6668990. doi: 10.1155/2021/6668990. eCollection 2021.
Zingiberis Rhizoma Recens (ZRR, the fresh rhizoma of Roscoe) is a widely used traditional Chinese medicine (TCM). It is also a traditional spice, widely used around the world. The present paper reviews advances in research relating to the botany, ethnopharmacology, phytochemistry, pharmacology, and toxicology of Zingiberis Rhizoma Recens. In addition, this review also discusses some significant issues and the potential direction of future research on Zingiberis Rhizoma Recens. More than 100 chemical compounds have been isolated from Zingiberis Rhizoma Recens, including gingerols, essential oils, diarylheptanoids, and other compounds. Modern studies have confirmed that Zingiberis Rhizoma Recens has pharmacological effects on the nervous system and cardiovascular and cerebrovascular systems, as well as antiemetic, antibacterial, antitumor, anti-inflammatory, and antioxidant effects. However, the modern studies of Zingiberis Rhizoma Recens are still not complete and more bioactive components and potential pharmacological effects need to be explored in the future. There is no unified standard to evaluate the quality and clinical efficacy of Zingiberis Rhizoma Recens. Therefore, we should establish reasonable, accurate, and reliable quality control standards to make better use of Zingiberis Rhizoma Recens.
生姜（ZRR，姜科植物姜的新鲜根茎）是一种广泛应用的传统中药。它也是一种传统香料，在世界各地广泛使用。本文综述了生姜在植物学、民族药理学、植物化学、药理学和毒理学方面的研究进展。此外，本综述还讨论了生姜研究中的一些重要问题以及未来研究的潜在方向。从生姜中已分离出100多种化合物，包括姜辣素、挥发油、二芳基庚烷类化合物和其他化合物。现代研究证实，生姜对神经系统、心血管和脑血管系统具有药理作用，还具有止吐、抗菌、抗肿瘤、抗炎和抗氧化作用。然而，生姜的现代研究仍不完整，未来需要探索更多的生物活性成分和潜在药理作用。目前尚无统一的标准来评价生姜的质量和临床疗效。因此，我们应建立合理、准确、可靠的质量控制标准，以便更好地利用生姜。
