Vodvárka P, Jancová J
Department of Radiotherapy, Regional Hospital Ostrava, Paskov, Czechoslovakia.
Neoplasma. 1988;35(2):243-50.
In this retrospective study on 226 patients with bladder cancer before radiotherapy following diagnostic or conservative surgery, bacterial infection of the urine was evaluated. The incidence of urine infection was 65.5%. 12.3% of the patients had sterile urine and in 22.1% of patients the investigation for urine infection was not performed. 77% of infections were caused by Gram-negative bacilli. No dependence of infection incidence on the tumor-T-stage, incidence of diabetes mellitus, prostatic gland size and tumor location near the internal ostium of the urethra was found. Thus, the cancer itself, transurethral diagnostic and/or transurethral or abdominal operation and the hospital stay appear to be of primary importance for the development of infection. To prevent serious late postradiation reactions it is important to manage infection before the start of radiotherapy. Some features of infection therapy in bladder cancer patients are discussed.
在这项针对226例膀胱癌患者的回顾性研究中，这些患者在诊断性或保守性手术后接受放疗前，对其尿液细菌感染情况进行了评估。尿液感染发生率为65.5%。12.3%的患者尿液无菌，22.1%的患者未进行尿液感染检查。77%的感染由革兰氏阴性杆菌引起。未发现感染发生率与肿瘤T分期、糖尿病发病率、前列腺大小以及尿道内口附近肿瘤位置有关。因此，癌症本身、经尿道诊断和/或经尿道或腹部手术以及住院时间似乎对感染的发生至关重要。为预防严重的放疗后晚期反应，在放疗开始前控制感染很重要。本文讨论了膀胱癌患者感染治疗的一些特点。
