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- 诱发性急性精神病:急性精神病的一种新病因。

-Induced Acute Psychosis: A Novel Cause of Acute Psychosis.

作者信息

Obuaya Chi-Chi, Gangatharan Gayathri Thivyaa, Karra Efthimia

机构信息

CNWL NHS Foundation Trust, London, UK.

Imperial College London School of Medicine, London, UK.

出版信息

Case Rep Infect Dis. 2021 Mar 4;2021:6649717. doi: 10.1155/2021/6649717. eCollection 2021.

Abstract

BACKGROUND

Infections have long been linked to psychosis and categorised within "secondary" psychoses. To date, there have been few reports of psychosis linked to brucellosis. This case report aims to present one such case. . A 31-year-old man was admitted to a general hospital with pyrexia, severe right upper quadrant pain, and an acute psychosis following a two-week holiday in South East Asia and the Mediterranean. Serological tests revealed that he had brucellosis. Following antibiotic treatment, the psychotic symptoms abated and he was discharged within ten days of hospitalisation.

CONCLUSIONS

This case of organic psychosis highlights the importance of considering brucellosis as a rare cause of acute psychosis. The exact mechanism of -induced psychosis remains unclear.

摘要

背景

感染长期以来一直与精神病相关联,并被归类为“继发性”精神病。迄今为止,与布鲁氏菌病相关的精神病报告很少。本病例报告旨在呈现这样一个病例。一名31岁男性在东南亚和地中海度过两周假期后,因发热、严重右上腹疼痛和急性精神病入住一家综合医院。血清学检查显示他患有布鲁氏菌病。经过抗生素治疗,精神病症状减轻,他在住院十天内出院。

结论

这例器质性精神病病例凸显了将布鲁氏菌病视为急性精神病罕见病因的重要性。感染诱发精神病的确切机制仍不清楚。

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本文引用的文献

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Neurobrucellosis Presenting as Acute Psychosis.以急性精神病为表现的神经型布鲁氏菌病
J Neurosci Rural Pract. 2018 Oct-Dec;9(4):644-646. doi: 10.4103/jnrp.jnrp_16_18.
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Organic psychosis: The pathobiology and treatment of delusions.有机精神病:妄想的病理生物学和治疗。
CNS Neurosci Ther. 2018 Jul;24(7):598-603. doi: 10.1111/cns.12973. Epub 2018 May 15.
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Microbial modulation of host apoptosis and pyroptosis.微生物对宿主细胞凋亡和焦亡的调节。
Front Cell Infect Microbiol. 2014 Jun 19;4:83. doi: 10.3389/fcimb.2014.00083. eCollection 2014.
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Immune system disturbances in schizophrenia.精神分裂症中的免疫系统紊乱。
Biol Psychiatry. 2014 Feb 15;75(4):316-23. doi: 10.1016/j.biopsych.2013.06.010. Epub 2013 Jul 25.
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Secondary psychoses: an update.继发性精神病:最新进展。
World Psychiatry. 2013 Feb;12(1):4-15. doi: 10.1002/wps.20001.

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