Amireskandari Annahita, Bean Andrew, Mauger Thomas
Department of Ophthalmology and Visual Sciences, West Virginia University, Morgantown, WV, USA.
Case Rep Ophthalmol Med. 2021 Mar 2;2021:5526097. doi: 10.1155/2021/5526097. eCollection 2021.
A case of severe anterior segment toxicity secondary to high-volume, undiluted intracameral moxifloxacin for endophthalmitis prophylaxis is reported. We examine the other reported cases of toxicity after intracameral moxifloxacin, as well as iris depigmentation and transillumination syndromes after oral and topical fluoroquinolone exposure. Additionally, we review the literature on safety, efficacy, and appropriate dosing of intracameral antibiotics with a focus on moxifloxacin.
报告了1例因使用高容量、未稀释的前房内莫西沙星预防眼内炎而继发严重眼前节毒性的病例。我们研究了其他已报道的前房内注射莫西沙星后出现毒性的病例,以及口服和局部使用氟喹诺酮类药物后出现的虹膜色素脱失和透照综合征。此外,我们回顾了关于前房内抗生素安全性、有效性和适当剂量的文献,重点是莫西沙星。