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Pharmacological Management of Osteoporosis in Postmenopausal Women: An Endocrine Society* Clinical Practice Guideline.绝经后妇女骨质疏松症的药物治疗:内分泌学会临床实践指南*。
J Clin Endocrinol Metab. 2019 May 1;104(5):1595-1622. doi: 10.1210/jc.2019-00221.
2
Calcium and vitamin D in bone fracture healing and post-traumatic bone turnover.钙和维生素 D 在骨折愈合和创伤后骨转换中的作用。
Eur Cell Mater. 2018 Jun 22;35:365-385. doi: 10.22203/eCM.v035a25.
3
Association Between Calcium or Vitamin D Supplementation and Fracture Incidence in Community-Dwelling Older Adults: A Systematic Review and Meta-analysis.补充钙或维生素D与社区居住老年人骨折发生率之间的关联:一项系统评价和荟萃分析。
JAMA. 2017 Dec 26;318(24):2466-2482. doi: 10.1001/jama.2017.19344.
4
Global dietary calcium intake among adults: a systematic review.全球成年人膳食钙摄入量:系统评价。
Osteoporos Int. 2017 Dec;28(12):3315-3324. doi: 10.1007/s00198-017-4230-x. Epub 2017 Oct 12.
5
Dietary patterns with special reference to calcium intake in 2-16-year-old Urban Western Indian children.2-16 岁城市西部印度儿童的特殊钙摄入量饮食模式。
Indian J Public Health. 2017 Jul-Sep;61(3):188-193. doi: 10.4103/ijph.IJPH_85_16.
6
Prevention and Treatment of Vitamin D and Calcium Deficiency in Children and Adolescents: Indian Academy of Pediatrics (IAP) Guidelines.儿童和青少年维生素D与钙缺乏的预防和治疗:印度儿科学会(IAP)指南
Indian Pediatr. 2017 Jul 15;54(7):567-573. doi: 10.1007/s13312-017-1070-x.
7
Effective treatment options for musculoskeletal pain in primary care: A systematic overview of current evidence.基层医疗中肌肉骨骼疼痛的有效治疗选择:当前证据的系统综述
PLoS One. 2017 Jun 22;12(6):e0178621. doi: 10.1371/journal.pone.0178621. eCollection 2017.
8
Dietary calcium intake and risk of cardiovascular disease, stroke, and fracture in a population with low calcium intake.钙摄入量低的人群中膳食钙摄入量与心血管疾病、中风和骨折风险的关系
Am J Clin Nutr. 2017 Jul;106(1):27-34. doi: 10.3945/ajcn.116.148171. Epub 2017 Jun 14.
9
Treatment of Low Bone Density or Osteoporosis to Prevent Fractures in Men and Women: A Clinical Practice Guideline Update From the American College of Physicians.治疗男性和女性的低骨密度或骨质疏松症以预防骨折:美国医师学院临床实践指南更新。
Ann Intern Med. 2017 Jun 6;166(11):818-839. doi: 10.7326/M15-1361. Epub 2017 May 9.
10
Calcium and Calcium Salts.钙及钙盐
J Assoc Physicians India. 2017 Feb;65(2):100-103.

印度骨科医生的钙处方:一项调查及文献综述

Calcium prescription by Indian orthopaedic surgeons: A survey and a review of literature.

作者信息

Sheth Binoti, Akil Prabhakar S, Pawar Pankaj, Ganwir Himanshu, Panchal Sameer, Jain Akash

机构信息

Department of Orthopaedics, Lokmanya Tilak Municipal Medical College and Hospital, 1st floor College Building, LTMC Hospital, Dr Babasaheb Ambedkar Rd, RB2 Central Railway Quarters, Sion West, Sion, Mumbai, Maharashtra, 400022, India.

Department of Orthopaedics, KEM Hospital, 6th floor Department of Orthopaedics, MS Building, Acharya Donde Marg, Parel East, Parel, Mumbai, Maharashtra, 400012, India.

出版信息

J Clin Orthop Trauma. 2021 Feb 24;16:292-298. doi: 10.1016/j.jcot.2021.02.015. eCollection 2021 May.

DOI:10.1016/j.jcot.2021.02.015
PMID:33747782
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7972954/
Abstract

BACKGROUND

Orthopaedic surgeons prefer calcium supplement for various pathologies like fracture, osteoporosis, chronic musculoskeletal pain, yet there is no proper evidence to support the benefits of taking them regularly. The average requirement for calcium is around 500-1000 mg/day for a healthy adult, this amount of calcium is not achieved by diet, especially in developing countries like India. Despite this, the serum calcium level remains unaltered, due to the well-controlled absorption and excretion of calcium by the human body. As there is no clarity over the dose, duration and the prefered calcium salts, we constructed a survey to find the preferred dose, duration, the preferred calcium salts among orthopaedic surgeons, and to give an in-depth review of literature about dose, duration, timing, preferred calcium salt and various other calcium-related queries.

MATERIALS AND METHOD

The survey included 15 pre-structured questionnaires; these questions were formatted and validated by senior surgeons and other specialists after a through a review of calcium-related literature. These questionnaires were used in a pilot study conducted within the department and were later modified and separated into 7 sections. Data were collected by both online survey (google forms) and direct interviews.

RESULT AND CONCLUSION

128 Orthopedic surgeons responded. The total number of response obtained was 2355. Unanswered questions were 152. From the survey, it was found that most orthopaedic surgeons prefer to prescribe calcium routinely (55.46%). The commonly used calcium salt was calcium carbonate (47.65%), followed by citrate (32.8%). 42.18% were not aware of the efficiency of prescribing calcium in divided doses. Most responded that calcium is not to be given for patients with renal stones, but literature shows that calcium prescribed reduces the recurrence of commonest kidney stones, calcium oxalate stones.

摘要

背景

骨科医生倾向于为骨折、骨质疏松症、慢性肌肉骨骼疼痛等各种病症开具补钙药物,但尚无充分证据支持定期服用钙剂的益处。健康成年人的钙平均需求量约为每日500 - 1000毫克,而通过饮食无法达到这个钙量,尤其是在印度等发展中国家。尽管如此,由于人体对钙的吸收和排泄得到良好控制,血清钙水平仍保持不变。由于钙剂的剂量、疗程以及首选钙盐尚无明确结论,我们开展了一项调查,以了解骨科医生对钙剂的首选剂量、疗程、首选钙盐,并对关于剂量、疗程、服用时间、首选钙盐以及其他各种与钙相关问题的文献进行深入综述。

材料与方法

该调查包括15份预先设计好的问卷;这些问题经资深外科医生和其他专家在全面回顾钙相关文献后进行了格式编排和验证。这些问卷在科室内部进行的一项试点研究中使用,随后进行了修改并分为7个部分。数据通过在线调查(谷歌表单)和直接访谈收集。

结果与结论

128名骨科医生做出了回应。获得的回应总数为2355份。未回答的问题有152个。从调查中发现,大多数骨科医生倾向于常规开具钙剂(55.46%)。常用的钙盐是碳酸钙(47.65%),其次是柠檬酸盐(32.8%)。42.18%的人不知道分剂量开具钙剂的有效性。大多数人认为肾结石患者不应服用钙剂,但文献表明,开具的钙剂可降低最常见的肾结石——草酸钙结石的复发率。