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硬膜外镇痛联合硬膜外羟乙基淀粉预防硬膜穿刺后头痛:20例病例报告及文献综述

Epidural analgesia followed by epidural hydroxyethyl starch prevented post-dural puncture headache: Twenty case reports and a review of the literature.

作者信息

Song Lin-Lin, Zhou Yin, Geng Zhi-Yu

机构信息

Department of Anesthesiology, Peking University First Hospital, Beijing 100034, China.

出版信息

World J Clin Cases. 2021 Mar 16;9(8):1946-1952. doi: 10.12998/wjcc.v9.i8.1946.

Abstract

BACKGROUND

Accidental dural puncture (ADP) and subsequent post-dural puncture headache (PDPH) remain common complications of epidural procedures for obstetric anesthesia and analgesia. No clear consensus exists on the best way to prevent PDPH after ADP.

CASE SUMMARY

We report our findings in twenty parturients who underwent an incorporated strategy of epidural analgesia followed by epidural hydroxyethyl starch (HES) to prevent PDPH after ADP with a 16-gauge Tuohy needle during epidural procedures. ADP with a 16-gauge Tuohy needle occurred in nine parturients undergoing a cesarean section (CS) and in eleven parturients receiving labor analgesia. An epidural catheter was re-sited at the same or adjacent intervertebral space in all patients. After CS, the epidural catheter was used for postoperative pain relief over a 48-h period. After delivery in eleven cases, epidural infusion was maintained for 24 h. Thereafter, 15 mL of 6% HES 130/0.4 was administered the epidural catheter immediately prior to catheter removal. None of the parturients developed PDPH or neurologic deficits over a follow-up period of at least two months to up to one year postpartum.

CONCLUSION

An incorporated strategy of epidural analgesia followed by epidural hydroxyethyl starch may have great efficacy in preventing PDPH after ADP.

摘要

背景

意外硬膜穿破(ADP)及随后的硬膜穿破后头痛(PDPH)仍然是产科麻醉和镇痛硬膜外操作常见的并发症。对于ADP后预防PDPH的最佳方法尚无明确共识。

病例总结

我们报告了20例产妇的研究结果,这些产妇在硬膜外操作期间采用16G Tuohy针行硬膜外麻醉,随后使用硬膜外羟乙基淀粉(HES)预防ADP后发生PDPH。9例行剖宫产(CS)的产妇和11例接受分娩镇痛的产妇发生了16G Tuohy针意外硬膜穿破。所有患者均在同一或相邻椎间隙重新放置硬膜外导管。剖宫产术后,硬膜外导管用于术后48小时的疼痛缓解。11例分娩后,硬膜外输注维持24小时。此后,在拔除导管前立即经硬膜外导管给予15ml 6% HES 130/0.4。在产后至少两个月至一年的随访期内,无一例产妇发生PDPH或神经功能缺损。

结论

硬膜外麻醉后给予硬膜外羟乙基淀粉的联合策略可能对预防ADP后PDPH有显著效果。

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