阿尔及利亚原发性甲状旁腺功能亢进症手术的单中心经验。
Monocentric experience of primary hyperparathyroidism surgery in Algeria.
作者信息
Nouikes Zitouni Souad
机构信息
Faculty of Medicine, Badji Mokhtar Annaba University, Boulevard Mohamed Seddik Benyahia, Annaba, Algeria.
Department of Otolaryngology, Annaba University Hospital, Ibn Rochd, Seraidi Rd, Annaba, Algeria.
出版信息
Surg Open Sci. 2021 Feb 10;4:32-36. doi: 10.1016/j.sopen.2021.02.002. eCollection 2021 Apr.
INTRODUCTION
Primary hyperparathyroidism (PHPT) remains a relatively underdiagnosed disease in developing countries. The aim of this study was to assess the demographic, pathological, biochemical, and surgical characteristics of patients with primary hyperparathyroidism in a university hospital department of otolaryngology in eastern Algeria.
MATERIALS AND METHOD
We performed a retrospective analysis of the records of 62 patients operated in our department for primary hyperparathyroidism between January 2002 and December 2013.
RESULTS
The mean age was 47.7 ± 15 years with a female preponderance (88.7%). The mode of discovery was during a biological assessment for bone syndrome in 42% of cases. The mean calcemia was 2.92 ± 0.6 mmol/L, and the intact serum parathyroid hormone was 867.78 ± 954.50 pmol/L. A total of 54.8% of patients had bilateral neck exploration, and 45.2% had minimally invasive open parathyroidectomy. Postoperative complications were dominated by severe hypocalcemia and hungry bone syndrome.
CONCLUSION
The diagnosis of primary hyperparathyroidism in our country is late, and management is often performed after the appearance of bone and renal complications.
引言
在发展中国家，原发性甲状旁腺功能亢进症（PHPT）仍然是一种诊断相对不足的疾病。本研究的目的是评估阿尔及利亚东部一家大学医院耳鼻喉科原发性甲状旁腺功能亢进症患者的人口统计学、病理学、生化和手术特征。
材料与方法
我们对2002年1月至2013年12月期间在我院接受原发性甲状旁腺功能亢进症手术的62例患者的记录进行了回顾性分析。
结果
平均年龄为47.7±15岁，女性占优势（88.7%）。42%的病例是在对骨综合征进行生物学评估时发现的。平均血钙为2.92±0.6 mmol/L，血清完整甲状旁腺激素为867.78±954.50 pmol/L。共有54.8%的患者进行了双侧颈部探查，45.2%的患者进行了微创开放性甲状旁腺切除术。术后并发症主要为严重低钙血症和饥饿骨综合征。
结论
我国原发性甲状旁腺功能亢进症的诊断较晚，治疗往往在出现骨和肾并发症后进行。
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