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新冠病毒病:急诊科阿片类药物使用障碍治疗的新障碍。

COVID-19: A new barrier to treatment for opioid use disorder in the emergency department.

作者信息

Grunvald Warren, Herrington Ramsey, King Roz, Lamberson Miles, Mackey Scott, Maruti Sanchit, Rawson Richard, Wolfson Daniel

机构信息

University of Vermont Larner College of Medicine Burlington Vermont USA.

Division of Emergency Medicine, University of Vermont Larner College of Medicine Burlington Vermont USA.

出版信息

J Am Coll Emerg Physicians Open. 2021 Mar 17;2(2):e12403. doi: 10.1002/emp2.12403. eCollection 2021 Apr.

Abstract

OBJECTIVE

Start Treatment and Recover (STAR) is an emergency department (ED) program that expands access to medication for opioid use disorder by identifying patients with opioid use disorder and offering ED-initiated buprenorphine/naloxone and rapid access to outpatient treatment. We sought to determine the impacts of the coronavirus disease 2019 pandemic on STAR and the patients with opioid use disorder it serves.

METHODS

We conducted a retrospective review of records comparing 2 periods: pre-pandemic (February 1, 2019-February 29, 2020) and pandemic (March 1, 2020-May 31, 2020). Variables evaluated included the number of STAR enrollments, ED census, percentage of census screening positive for opioid use disorder, number and percentage of ED overdose visits, and overdose fatalities by month. All analyses were conducted using 2-sample tests to calculate the mean and 95% confidence intervals (CIs).

RESULTS

Comparing the pre-pandemic to the pandemic period, the mean monthly ED visits decreased from 5126.9 to 3306.7 (difference = -1820.3; 95% CI, -3406.3 to -234.2), STAR mean monthly enrollments decreased from 9.7 to 1.3 (difference = -8.4; 95% CI, -12.8 to -4.0), and statewide monthly opioid-related fatalities increased from 9.4 to 15.3 (difference = 5.9; 95% CI, 0.8 to 11.1). However, the percentage of individuals who presented to the ED with opioid use disorder or overdose remained unchanged.

CONCLUSION

Although overall ED visits declined during the pandemic period, the percentage of patients presenting with opioid use disorder or overdose remained constant, yet there was a dramatic decline in enrollment in ED-initiated medication for opioid use disorder and an increase in statewide monthly opioid-related fatalities. Strategies to maintain medication for opioid use disorder treatment options must be implemented for this vulnerable population during the ongoing pandemic.

摘要

目的

“启动治疗与康复”(STAR)是一项急诊科项目,通过识别阿片类物质使用障碍患者并提供急诊科启动的丁丙诺啡/纳洛酮以及快速获得门诊治疗,扩大了阿片类物质使用障碍患者获得药物治疗的机会。我们试图确定2019年冠状病毒病大流行对STAR及其所服务的阿片类物质使用障碍患者的影响。

方法

我们对两个时期的记录进行了回顾性比较:大流行前(2019年2月1日至2020年2月29日)和大流行期间(2020年3月1日至5月31日)。评估的变量包括STAR登记人数、急诊科普查人数、普查中阿片类物质使用障碍筛查呈阳性的百分比、急诊科过量用药就诊人数及百分比,以及按月统计的过量用药死亡人数。所有分析均使用双样本检验来计算均值和95%置信区间(CI)。

结果

将大流行前时期与大流行期间进行比较,每月急诊科就诊的平均人数从5126.9降至3306.7(差值 = -1820.3;95% CI,-3406.3至-234.2),STAR每月的平均登记人数从9.7降至1.3(差值 = -8.4;95% CI,-12.8至-4.0),全州每月与阿片类物质相关的死亡人数从9.4增至15.3(差值 = 5.9;95% CI,0.8至11.1)。然而,因阿片类物质使用障碍或过量用药前来急诊科就诊的患者百分比保持不变。

结论

尽管在大流行期间急诊科就诊总人数有所下降,但因阿片类物质使用障碍或过量用药前来就诊的患者百分比保持不变,然而,急诊科启动的阿片类物质使用障碍药物治疗登记人数大幅下降,全州每月与阿片类物质相关的死亡人数增加。在当前大流行期间,必须针对这一弱势群体实施维持阿片类物质使用障碍治疗药物选择的策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fa2/7967916/718c5f0d6ffd/EMP2-2-e12403-g003.jpg

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